Protein Alignment fab1 and Hsp60B

DIOPT Version :9

• Sequence 1: NP_611269.1
• Gene: fab1 / 37033
• FlyBaseID: FBgn0028741
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 121/607 - (19%)
• Similarity: 216/607 - (35%)
• Gaps: 142/607 - (23%)

  Fly  1222 TSDALAMARR-ALAES-IELWGPRLQEIEKLTAKQAHHIDSGTICTEELRPEQVQTADSSKVTTS 1284
            |.|...:||. ||.:. :.|....:|::...|.:.|   ..|| .|..:....:.....:::|..
  Fly    68 TKDGFTVARSIALKDQHMNLGAKLVQDVADNTNESA---GDGT-TTATVLARAIAKEGFNQITMG 128

  Fly  1285 SLPKE------------NDPLECPSEDTETGASNSQTVLDKNFSIDQMLASTVNVYSDKKSIRKI 1337
            :.|.|            .|.|:..|:..|| ....|.|...:.:.|..:...:...:||...|..
  Fly   129 ANPVEIRRGVMLAVDVVKDKLKEMSKAVET-REEIQQVATLSANGDTEIGRLIGEATDKVGPRGT 192

  Fly  1338 LTQLLPSG----NQVNPLQSPFPAQDHLTLPLGSI-PIHVRETDLSSV-IAYSLTSMDYQKAIDE 1396
            :|  :..|    :::|.:|.       |....|.: |..|..:..|.| .|.:|..:..:|....
  Fly   193 IT--VKDGKRLKDELNIIQG-------LRFDNGYVSPFFVNSSKGSKVEFANALVMISLKKITGL 248

  Fly  1397 AEANSNAAHSSPQLKRKIPLAESVSD------------------AEDSPSL----SRTSSNTSAA 1439
            ::.......|..|.:..|.:||.:|.                  |..|||.    .....:.|||
  Fly   249 SQIVKGLEQSLRQRRPLIIIAEDISGEALNALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAA 313

  Fly  1440 PNASVPSPATAASESEEKSKERIKQPPSPHITLAFQDHSCQFQCK-------IYFAREFDAMRSK 1497
            ..|::.......|:.||...|.:.|.....|:   :|.:...|.|       :...:..|.:..|
  Fly   314 TGATIFGDDINYSKMEEAKLEDLGQVGEAVIS---KDSTMLLQGKPKTGLLEMRIQQIQDELAEK 375

  Fly  1498 SLKPPKLDKSLYRRLEKSKMREELRISQSRTGSEMELVRKPSDVGAPRTTEDDSNQEEDARIALA 1562
            .:||.:.|: |.:||  |.:.:.:.:.....|||:|:                 |:::| |:..|
  Fly   376 QIKPEQRDR-LRQRL--SALTKGVAVLHIGGGSEVEV-----------------NEKKD-RVVDA 419

  Fly  1563 RSLCKSVQWEARGGKSGSRFCKTLDDRFVLKEMNSRDMTIFEPFAPKYFEYIDRCQQQQQP-TLL 1626
            .:..::...|......|:.|.:.:.   .|:|:.:....:     .|..:.:  |...:.| ..:
  Fly   420 LNATRAAIEEGIVPGGGTAFLRCIP---YLQELKTESADL-----QKGVDIV--CNALRMPCQTI 474

  Fly  1627 AKIFGVFRVSVKKKDSFVERSVMVMENLFYGCNIENKFDLKGSERNRLV-----DPSNQQGEIVL 1686
            |:..||             ...||:..:..|.. :..:|..|.|..|||     ||:.      :
  Fly   475 AQNAGV-------------DGPMVVAKVLNGSE-DYGYDAMGDEYCRLVEKGIIDPTK------V 519

  Fly  1687 LDENLVQMSWSKPLYVLSHSKTVLRDAIQRDSSFLEKNLVMDYSLLVGLDKKNGVLVLGIIDYIR 1751
            |...:...:....|  ||.::.|:.|:  |:...|.|.......:..|||...|    |:.:.
  Fly   520 LRTAITDAAGVASL--LSTTEVVITDS--RNDDLLSKLSGAGGGMDDGLDMNMG----GLEEL-- 574

  Fly  1752 TFTLDKRVESIIKGSGILGGKG 1773
                     :.:.|.|.:||.|
  Fly   575 ---------AALSGLGGMGGMG 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264
		DEP	329..397	CDD:214489
		Fab1_TCP	464..717	CDD:239450
		PIPKc	1413..1797	CDD:295374	79/396 (20%)
Hsp60B	NP_524925.1	PTZ00114	9..558	CDD:185455	111/561 (20%)
		GroEL	22..543	CDD:239460	107/544 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453472
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930