Protein Alignment fab1 and pip5k1bb

DIOPT Version :9

• Sequence 1: NP_611269.1
• Gene: fab1 / 37033
• FlyBaseID: FBgn0028741
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: XP_005166786.1
• Gene: pip5k1bb / 447840
• ZFINID: ZDB-GENE-040912-141
• Length: 528
• Species: Danio rerio
• Alignment Length: 479
• Identity: 102/479 - (21%)
• Similarity: 157/479 - (32%)
• Gaps: 145/479 - (30%)

  Fly  1397 AEANSNAAHSSPQLKRKIPLAESVSDAEDSP---SLSRTSSNTSAAPNASVPSPATAASESEEKS 1458
            :.||:|...||...:|:....::.|.|....   .:..|..|.::.|:..|........||....
Zfish     2 SSANANGVGSSGNNRREKTYKKTTSSALKGAIQLGIGYTVGNLTSKPDRDVLMQDFYVVESVFLP 66

  Fly  1459 KERIKQPPSPHITLAFQDHSCQFQCKIYFAREFDAMRSK-SLKPPKLDKSLYRRLEKSKMREELR 1522
            .|.....|:.|    :.|    |:.|.|....|...|.. .:||   |..||
Zfish    67 SEGSNLTPAHH----YPD----FRFKTYAPLAFRYFRELFGIKP---DDYLY------------- 107

  Fly  1523 ISQSRTGSEMELVRKPSDVGAPRTTEDDSNQEEDARIALARSLCKSVQWE-ARGGKSGSRFCKTL 1586
                                                     |:||....| :..|.|||.|..|.
Zfish   108 -----------------------------------------SICKEPLIELSNPGASGSLFYLTS 131

  Fly  1587 DDRFVLKEMNSRDMTIFEPFAPKYFEYIDRCQQQQQPTLLAKIFGVFRVSVKKKDSFVERSVMVM 1651
            ||.|::|.:..::....:...|.|:..::    |...|||.|.:|::.|    :...:...::||
Zfish   132 DDEFIIKTVQHKEAEFLQKLLPGYYMNLN----QNPRTLLPKFYGLYCV----QSGGINIRLVVM 188

  Fly  1652 ENLF-YGCNIENKFDLKGSERNRLVDPSNQQGEI-VLLDENLVQMSWSKPLYVLSHSKTVLRDAI 1714
            .|:. ....:..|:|||||...|......::... ...|.:.|.|  ...||....:...|...:
Zfish   189 NNVLPRSVKMHYKYDLKGSTYKRRASRKEREKPCPTYKDLDFVDM--HDGLYFDPETYNALMKTL 251

  Fly  1715 QRDSSFLEKNLVMDYSLLVGL-------------------------------------------- 1735
            |||...||...:||||||:|:
Zfish   252 QRDCRVLESFKIMDYSLLLGVHVLDQSHRDGDGSAVDGKRTVGQKVLYSTAMESIQGDGKAAEAL 316

  Fly  1736 ---DKKNGV-----------LVLGIIDYIRTFTLDKRVESIIKGSGILGGKGKDPTVVNPERYKQ 1786
               |...|:           :.|||||.::::...|::|...|.   |...|...:|..|..|..
Zfish   317 TTDDTMGGIPAKTHRDEKVLIFLGIIDILQSYRFIKKLEHSWKA---LVYDGDTVSVHRPSFYAN 378

  Fly  1787 RFIDAM-DRYF-LTVPDRWEGLSK 1808
            ||:..| .|.| ...|:|:....|
Zfish   379 RFLKFMSSRVFRKNQPNRFSPSKK 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264
		DEP	329..397	CDD:214489
		Fab1_TCP	464..717	CDD:239450
		PIPKc	1413..1797	CDD:295374	93/450 (21%)
pip5k1bb	XP_005166786.1	PIPKc	53..386	CDD:214623	85/410 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810