Protein Alignment fab1 and sktl

DIOPT Version :9

• Sequence 1: NP_611269.1
• Gene: fab1 / 37033
• FlyBaseID: FBgn0028741
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_001286646.1
• Gene: sktl / 37356
• FlyBaseID: FBgn0016984
• Length: 792
• Species: Drosophila melanogaster
• Alignment Length: 679
• Identity: 131/679 - (19%)
• Similarity: 210/679 - (30%)
• Gaps: 264/679 - (38%)

  Fly  1267 ELRPEQVQTADSSKVTTSSLPKENDPLECPSEDTETGASNSQTVLDKNFSIDQMLASTVNVYSDK 1331
            ||..|.|...|..|   .....||:|||            :|..|::..
  Fly     6 ELELEPVGKQDRLK---DQPDDENEPLE------------NQLELEQEH---------------- 39

  Fly  1332 KSIRKILTQL-LPSGNQVNPLQSPFPAQDHLTLPLGSIPIHVRETDLSSVIAY---SLTSMDYQK 1392
               :.:||.: :|.....:|.|...|:...   |:...|...|:....:.:|:   ..||:..|
  Fly    40 ---KSLLTPVKIPPAQTASPDQEATPSTPP---PMSLQPGTSRQLFRDAAMAHGGQETTSLLQQ- 97

  Fly  1393 AIDEAEANSNAAHSSPQLKRKIPLAESVSDAEDSPSLSRTSSNTSAAPNASVPSPATAASESEEK 1457
                 |.|:.||..:|  ..|:..|.|..||    |:||              :|:|...:.|:|
  Fly    98 -----ELNNIAATQTP--ASKLRSASSTLDA----SISR--------------NPSTTGGKHEKK 137

  Fly  1458 SKERIKQPPSPHITLAFQDHSCQFQCKIYFAREFDAMRSKSLKPPKLDKSLYRRLEKSKMREELR 1522
            ...| :......:|                                     |::::..::...::
  Fly   138 LGHR-RVAEGGEVT-------------------------------------YKKIQSKQIMGSIQ 164

  Fly  1523 IS-QSRTGS---------------EMELVRKPSDVGA--PRTTEDDSNQEEDARIA--------- 1560
            :. |...||               |||.:..|.|..:  |....:|...:..|.||
  Fly   165 LGIQHTVGSLASKPKRDLLMNDFWEMETISFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLFG 229

  Fly  1561 -----LARSLCKSVQWE-ARGGKSGSRFCKTLDDRFVLKEMNSRDMTIFEPFAPKYFEYIDRCQQ 1619
                 ...|:|.|...| :..|.|||.|..|.||.|::|.:..::....:...|.|:..:    .
  Fly   230 IAPDDFLMSMCASPLRELSNPGASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNL----S 290

  Fly  1620 QQQPTLLAKIFGVFRVSVKKKDSFVERSVMVMENLF-YGCNIENKFDLKGSE-RNRLVDPSNQQG 1682
            |...|||.|.||::......|:.    .::.|.||. ....:..|:|||||. |.:......|:.
  Fly   291 QNPRTLLPKFFGLYCFHYNSKNV----RLVAMNNLLPSDIKMHCKYDLKGSSFRRKASKAERQKA 351

  Fly  1683 EIVLLDENLVQMSWSKPLYVLSHSKTVLRDAIQRDSSFLEKNLVMDYSLLVG------------- 1734
            .....|.:..: .....:::.:.....|...|:||...||...:||||||||
  Fly   352 SPTFKDLDFAE-HHPNGIFLETDKYNALMSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKRE 415

  Fly  1735 ---------LDKKNG-------------------------------------------------- 1740
                     |.:|..
  Fly   416 ERILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQR 480

  Fly  1741 ----------------------------------------VLVLGIIDYIRTFTLDKRVESIIKG 1765
                                                    :|.:||||.::::.|:|::|...|
  Fly   481 LVAHSTALESITADMDVPLEEDEDVPAGGIPARSENDERLILYIGIIDILQSYRLEKKLEHTFK- 544

  Fly  1766 SGILGGKGKDPTVVNPERYKQRFIDAMDR 1794
             .|| ..|...:|..|..|.:||.|||.:
  Fly   545 -SIL-YNGDTVSVCRPSFYAKRFQDAMGK 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264
		DEP	329..397	CDD:214489
		Fab1_TCP	464..717	CDD:239450
		PIPKc	1413..1797	CDD:295374	100/529 (19%)
sktl	NP_001286646.1	PIPKc	183..573	CDD:214623	82/401 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810