Protein Alignment fab1 and CCT4

DIOPT Version :10

• Sequence 1: NP_611269.1
• Gene: fab1 / 37033
• FlyBaseID: FBgn0028741
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 526
• Identity: 118/526 - (22%)
• Similarity: 195/526 - (37%)
• Gaps: 146/526 - (27%)

  Fly   316 DDRKNILQQSNSLITLHEEMQRDLPAQNCGQRLIEFLNSNNKSANE--VQAVAILNAMLAAGFLE 378
            :|...||:|.|   .||       ||   .:.|:|...:.:.:|.:  ...|.|..|:|.|  .|
  Fly    65 NDGATILKQMN---VLH-------PA---AKMLVELSRAQDVAAGDGTTSVVVIAGALLEA--CE 114

  Fly   379 PIVPDPEQMDFDSSLHYKFSKSSSSDTSRTMSPQFEANPHAEPQPPKSMDQSAEEKEKELENELE 443
            .::        ...||    .::.||:.:..|                  ..|.|..|::...:|
  Fly   115 KLL--------QKGLH----PTAISDSFQRCS------------------NKAVEILKQMSTPIE 149

  Fly   444 NDRCYT---TATSKLLASYCEHEEQLLAQMLRAHNLDQEWDKVLQMLCSTAANHFKP-EHCSNDL 504
            .|...|   :|::.|.:.....:..|||.:        ..|.||::.        .| :..|.||
  Fly   150 LDDRETLIKSASTSLNSKVVSQQSSLLAPI--------AVDAVLKVT--------DPGKETSVDL 198

  Fly   505 MDIRNYVNFKKVPGGRRKDSKIVHGVAFSKNVAHKDMATHVPFPRILLLQCPIV-------YERI 562
            .:|:...:.    ||..:|:::|.|:.|:...|..:....:...:|.|:|..|.       :..|
  Fly   199 KNIKVISSL----GGTVEDTELVDGLVFTCRSAGSNAPKRIEKAKIGLIQFCISAPKTDMDHNVI 259

  Fly   563 EGKFVTIETVLLQEKEYLRNVCARIMSFKPNVVLVHKN-----VAGIAQDLLRSYEVTLVLDVKL 622
            ...:..::.||.:|:.|:.|:..:|.....||:||.|:     |:.:||..|...:..:|.||:.
  Fly   260 VSDYAAMDRVLKEERSYILNIVKQIKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVER 324

  Fly   623 SVMERLSRTLQCDIVSSIESNITMPKLGYCNDFYIRNYNGKTLM--------FFEKLTN----PR 675
            ..:|.:.:||.|..::|::            .|...|.:...|:        .|.|:|.    .|
  Fly   325 EDIEFVCKTLHCRPIASLD------------HFTAENLSSADLVEEVASGTNKFVKITGIQNMGR 377

  Fly   676 GYTCLLRGGSNAELTRVKR-VASALLFARYNWRL------------EMSFLLNEFAQPLSPKP-- 725
            ..:.:.||.:...|....| :..||...|...:|            ||:..|...||.:....
  Fly   378 TVSIICRGSNKLVLEEAARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAY 442

  Fly   726 ---SIFDSKETSPKT----------ETEAELRS------KRPIILERKSEDKITTIVSENVSDFT 771
               :..|:.|..|.|          .|..|||:      |...|..||.  .||.|.:|||   .
  Fly   443 CFRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRKG--AITDIFAENV---V 502

  Fly   772 DPLRAS 777
            .||..|
  Fly   503 QPLLVS 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264
		DEP	329..397	CDD:214489	15/69 (22%)
		Fab1_TCP	464..717	CDD:239450	64/290 (22%)
		PIPKc_PIKfyve	1479..1796	CDD:340437
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	118/526 (22%)