DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fab1 and SPBC9B6.03

DIOPT Version :9

Sequence 1:	NP_611269.1	Gene:	fab1 / 37033	FlyBaseID:	FBgn0028741	Length:	1809	Species:	Drosophila melanogaster
Sequence 2:	NP_595745.1	Gene:	SPBC9B6.03 / 2540208	PomBaseID:	SPBC9B6.03	Length:	293	Species:	Schizosaccharomyces pombe

Alignment Length:	271	Identity:	63/271 - (23%)
Similarity:	99/271 - (36%)	Gaps:	56/271 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 QSYNTVNDISSGSSSSSSTQPVQVVGKSQFFSDSQTSTAEIADVETSSQSSVRPQPPTTLSIRTN 113
            |:.|....:|...:|||::.|.           :|.|.....:.:..|..:.:.:|....|...|
pombe    42 QATNGTGSVSGSPNSSSNSTPA-----------NQGSLPSHTNPQLYSSITRKERPELFRSYSGN 95

  Fly   114 SETRGTSTSSNTAAEDSETSDRVETLPLPTSEANQGRTVSNVLKHISNIVATKNNNDLRNYKDTE 178
            ........||..||.....|.:..:..:..:..|..             |||..|  .::.::|.
pombe    96 PRLSKPYASSKLAASSRTASYQAMSYSVSPTSTNSS-------------VATSLN--YQSSRETG 145

  Fly   179 LQR-FWMPDSKAKECY--DCSQKFSTFRRKHHCRLCGQIFCSKCCNQVVPGMIIRCDGDLKVC-- 238
            :.: .|.|||....|.  .||.:|..|.|:||||.||.|||:..|::.:|..:     |:|.|
pombe   146 ISKDHWKPDSDVSVCSFPSCSVRFGLFDRRHHCRRCGDIFCALHCDRNIPLTM-----DVKFCLA 205

  Fly   239 ----NYCSKIVLTFLKSSSSEMGQDMQELQQHLSNKLEVQDS---GSSLAKHPQMQ-----RAPL 291
                ..|......:||..        |.:....||.:.|.:|   ......||..|     ..|:
pombe   206 GSLYRSCVSCFYEYLKWK--------QSIDLASSNDITVIESTIAPQQATTHPPSQPKNAVSVPI 262

  Fly   292 PRKTSVGYQEE 302
            |:..|...:.|
pombe   263 PKMDSTDSKGE 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264	25/68 (37%)
		DEP	329..397	CDD:214489
		Fab1_TCP	464..717	CDD:239450
		PIPKc	1413..1797	CDD:295374
SPBC9B6.03	NP_595745.1	FYVE_scVPS27p_Vac1p_like	159..216	CDD:277275	21/61 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2108
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030