Protein Alignment fab1 and Zfyve28

DIOPT Version :9

• Sequence 1: NP_611269.1
• Gene: fab1 / 37033
• FlyBaseID: FBgn0028741
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_001015039.1
• Gene: Zfyve28 / 231125
• MGIID: 2684992
• Length: 905
• Species: Mus musculus
• Alignment Length: 291
• Identity: 61/291 - (20%)
• Similarity: 97/291 - (33%)
• Gaps: 93/291 - (31%)

  Fly    55 NDISSGSSSSSSTQPVQVVGKSQFF---SDSQTSTAE----IADVETSSQSSVRPQPPTTLSIRT 112
            :|::..:..:|:.|..:....|:..   |..|..||.    ..:|:...:...|.|.|....:.:
Mouse   619 SDVTLPAEDASNRQEPKAPASSKCLAHTSGPQVDTASRLQGEGEVKGQPEPEARKQDPEKSPVVS 683

  Fly   113 NSETRGTST---------SSNTAAEDSETSDRVE-------TLPLPTSE---------------- 145
            ....||...         ||:|....|..:.|::       ..|:.|.|
Mouse   684 GDSPRGDVAQTEHQHLLGSSSTVGSCSLDNTRLDVATAAMPVTPMATREKIRSRFHGSHDLIHRL 748

  Fly   146 ------------ANQGRTVSNVLKHISNIVATKNNND-----------LRNYK------------ 175
                        .|....:.::||.:..::|||...|           ||:..
Mouse   749 FVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLKKVTQTLRSAALEDCALCQETVS 813

  Fly   176 -----------DTELQRFWMPDSKAKECYDCSQKFSTFRRKHHCRLCGQIFCSKCCNQVVP---- 225
                       |.|....|:||.....|..|...|:..|||||||.||:||||:|.:...|
Mouse   814 SSELAAKTRDGDFEDPPEWVPDEACGFCTSCKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRY 878

  Fly   226 GMIIRCDGDLKVCNYCSKIVLTFLKSSSSEM 256
            |.:    ..::||.:|....:|...|..:.|
Mouse   879 GQV----KPVRVCTHCYMFHVTPFYSDKTGM 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264	25/64 (39%)
		DEP	329..397	CDD:214489
		Fab1_TCP	464..717	CDD:239450
		PIPKc	1413..1797	CDD:295374
Zfyve28	NP_001015039.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	354..441
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	516..552
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	589..691		14/71 (20%)
		FYVE_LST2	828..892	CDD:277270	25/67 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2108
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030