Protein Alignment fab1 and ppk-2

DIOPT Version :9

• Sequence 1: NP_611269.1
• Gene: fab1 / 37033
• FlyBaseID: FBgn0028741
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_497500.1
• Gene: ppk-2 / 175344
• WormBaseID: WBGene00004088
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 284
• Identity: 60/284 - (21%)
• Similarity: 119/284 - (41%)
• Gaps: 79/284 - (27%)

  Fly  1578 SGSRFCKTLDDRFVLKEMNSRDMTIFEPFAPKYFEYIDRCQQQQQPTLLAKIFGVFRVSVKKKDS 1642
            |..||..:.|.:||:|.|:|..:.........|.:|:   .::|..|||.:..|::|::::..::
 Worm   127 STPRFFISYDKKFVIKSMDSEAVAELHSVLRNYHQYV---VEKQGKTLLPQYLGLYRLTIEGSET 188

  Fly  1643 FVERSVMVMENLF---YGCNIENKFDLKGSERNRLVDPSNQQGEI-VLLDENLVQMSWSKPLYVL 1703
            :    ::||.|:|   ||  :..|||||||..:|......:..:: .|.|.:.::.:|.  |.:.
 Worm   189 Y----LIVMRNVFGRKYG--VHTKFDLKGSTVSRAASDKEKAKDLPTLKDNDFLEQNWK--LNLP 245

  Fly  1704 SHSKTVLRDAIQRDSSFLEKNLVMDYSLLVGLD-------------------------------- 1736
            ..:..:|.:.:..|:.:|.:..:||||||||:.
 Worm   246 PEAGKLLIEMLTSDTEWLTRMHLMDYSLLVGIHDCERAAQEAANRPVEQNSEESGDELAPTPPDS 310

  Fly  1737 -------------------------------KKNGVLVLGIIDYIRTFTLDKRVESIIKGSGILG 1770
                                           :||.:..:|::|.:..:.:.||..:..| :...|
 Worm   311 PIPSTGGAFPGVSGGPDLDDEFYAIASPADFEKNLIYFIGLVDILTYYGIKKRSATAAK-TVKYG 374

  Fly  1771 GKGKDPTVVNPERYKQRFIDAMDR 1794
            ...::.:.|.||:|.:|.::.:.|
 Worm   375 SDAENISTVKPEQYAKRLVEFVSR 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fab1	NP_611269.1	FYVE_PIKfyve_Fab1	182..243	CDD:277264
		DEP	329..397	CDD:214489
		Fab1_TCP	464..717	CDD:239450
		PIPKc	1413..1797	CDD:295374	60/284 (21%)
ppk-2	NP_497500.1	PIPKc_PIP5KII	30..398	CDD:340442	59/282 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810