DRSC/TRiP Functional Genomics Resources

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Protein Alignment fab1 and Pip4k2c

DIOPT Version :9

Sequence 1:NP_611269.1 Gene:fab1 / 37033 FlyBaseID:FBgn0028741 Length:1809 Species:Drosophila melanogaster
Sequence 2:XP_011241590.1 Gene:Pip4k2c / 117150 MGIID:2152214 Length:484 Species:Mus musculus


Alignment Length:243 Identity:66/243 - (27%)
Similarity:107/243 - (44%) Gaps:57/243 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly  1564 SLCKSVQWEARGGKSGSRFCKTLDDRFVLKEMNSRDMTIFEPFAPKYFEYIDRCQQQQQPTLLAK 1628
            ||.:|...|..|  |..||..:.|...|:||::|.|:.........|.:||.:|...   |||.:
Mouse   183 SLTRSPPSETEG--SDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGN---TLLPQ 242

  Fly  1629 IFGVFRVSVKKKDSFVERSVMVMENLF-YGCNIENKFDLKGSERNRLVDPSNQQGEIVLLDENLV 1692
            ..|::||||:.:||:    ::||.|:| :...:..|:|||||..:|......:..|:..| :::.
Mouse   243 FLGMYRVSVENEDSY----MLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL-KDMD 302

  Fly  1693 QMSWSKPLYVLSHSKTVLRDAIQRDSSFLEKNLVMDYSLLVGLDKKNGVLVLGIIDYIRTFTLDK 1757
            .::.::.:|:....|.|..:.::||..||.:..:||||||           |||.|.||      
Mouse   303 FLNKNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLL-----------LGIHDIIR------ 350

  Fly  1758 RVESIIKGSGILGGKGKDPTVVNPERYKQRFIDAMDRYFLTVPDRWEG 1805
                           |.:|....|.|.::              ..|:|
Mouse   351 ---------------GSEPEEEGPVREEE--------------SEWDG 369

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fab1NP_611269.1 FYVE_PIKfyve_Fab1 182..243 CDD:277264
DEP 329..397 CDD:214489
Fab1_TCP 464..717 CDD:239450
PIPKc 1413..1797 CDD:295374 64/233 (27%)
Pip4k2cXP_011241590.1 PIPKc 117..349 CDD:391950 58/186 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5253
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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