Protein Alignment OstDelta and RPN2

DIOPT Version :9

• Sequence 1: NP_611265.1
• Gene: OstDelta / 37029
• FlyBaseID: FBgn0034277
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001311230.1
• Gene: RPN2 / 6185
• HGNCID: 10382
• Length: 663
• Species: Homo sapiens
• Alignment Length: 671
• Identity: 222/671 - (33%)
• Similarity: 331/671 - (49%)
• Gaps: 74/671 - (11%)

  Fly     7 VIFCVLVASGPTWSARTVDSHLGQKDLSRLQKVFVDGFGSSDLQSIFF-----SSLNIQLTDATQ 66
            |....|.....|| |.|...:|.:.|:.||:......|  ::|:|.|:     |||..|:.||
Human     9 VFLLALTIIASTW-ALTPTHYLTKHDVERLKASLDRPF--TNLESAFYSIVGLSSLGAQVPDA-- 68

  Fly    67 KEPLCKKIATLHSESKLNSFEKD--YYYIGASRNL-GCSAKID----EGLLSKVYSSLNSELGSS 124
                 ||..| :..|.|:....|  :|...||:.| ||...|.    :.||:.|     ||..|.
Human    69 -----KKACT-YIRSNLDPSNVDSLFYAAQASQALSGCEISISNETKDLLLAAV-----SEDSSV 122

  Fly   125 QEIFYRVVTHKVLGVEINEATQEKLVKRLQELLKKDDTLSGLG---------------YAFNVAP 174
            .:|::.|......|:.:  |:||.|......|.|::..|:.:.               .|...|.
Human   123 TQIYHAVAALSGFGLPL--ASQEALSALTARLSKEETVLARVWSTVLESRSLFSKRTVQALQTAS 185

  Fly   175 LLGASASF--IANRVEDAIVQADEVDGKLLQFEGGLSITSLIINGAFGVSKTFNKPVPITADQAV 237
            .|...|..  |...:||.:.:.||:.|..||||.||..|:|.:...:.:.........|..||.:
Human   186 HLSQQADLRSIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSIKEDQVI 250

  Fly   238 KFANYFLSRRSVQTAKGAHVLIEALKTISGADKIAPVCVQLIGNGQLDAQSPTLNVAVVDLLGKP 302
            :..|...|:::.::...|..:..|...:|......||.|...|:.....:...|.:.|.::|.:|
Human   251 QLMNAIFSKKNFESLSEAFSVASAAAVLSHNRYHVPVVVVPEGSASDTHEQAILRLQVTNVLSQP 315

  Fly   303 LSPAPKVINAKVIRKKDSSVLADKITVASKSSDKTTYVADLASL-----KPARGVYQ--AELSAD 360
            |:.|       .::.:.:..:|.:.||..|:|  .|.|.|:..|     |.:.|.|.  .|:..|
Human   316 LTQA-------TVKLEHAKSVASRATVLQKTS--FTPVGDVFELNFMNVKFSSGYYDFLVEVEGD 371

  Fly   361 GVY---TQTLQFKVLGRVKVQSLEVGIAESDASAATRKQSVTYPGKLQEVLSADSTQKLLLKAVL 422
            ..|   |..|:.|:...|.:.::::...:.|.|.|.:...||||.|.:....|||.|...|...|
Human   372 NRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQL 436

  Fly   423 VDESTSKPLAVHQAFVRLYNKKTDKEIIFVAEQDSSKAYKFDMDVGNNGKNFNYQSGTYSIYLTV 487
            ||.:|...|..||.||||:|:||.:|::||||.|:...|||::|.......|:..||||::||.:
Human   437 VDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLII 501

  Fly   488 GDSSLSNSFEWLVAEVQLKFNEDK---EVKPKNTSGPLPEIIHQFRVPDKRPPRIVSDIFTGLCI 549
            ||::|.|...|.||:|.:||.|::   .|..:|...|..||.|.||.|:||||.:||:.||.|.:
Human   502 GDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALIL 566

  Fly   550 TPLVLLFVFWGKLGINVSNLTLAPSTIGFHLGFGGILVLFFVFWLQLNMFQTLRLLIPIAVFTFL 614
            :||:|||..|.::|.||||.|.|||||.||||...:|.|.:|:|.||||||||:.|..:...|||
Human   567 SPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAILGSVTFL 631

  Fly   615 AGNRLL-----RRLYAQRNSK 630
            ||||:|     :|:.|:::|:
Human   632 AGNRMLAQQAVKRIAAEQSSR 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OstDelta	NP_611265.1	Ribophorin_II	8..623	CDD:283474	218/661 (33%)
RPN2	NP_001311230.1	Ribophorin_II	9..639	CDD:283474	219/656 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159605
Domainoid	1	1.000	299	1.000	Domainoid score	I1449
eggNOG	1	0.900	-	-		E1_KOG2447
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2214
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2695
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55779
OrthoDB	1	1.010	-	-		D1001599at2759
OrthoFinder	1	1.000	-	-		FOG0005725
OrthoInspector	1	1.000	-	-		oto91370
orthoMCL	1	0.900	-	-		OOG6_103527
Panther	1	1.100	-	-	LDO	PTHR12640
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3628
SonicParanoid	1	1.000	-	-		X4716
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800