DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5009 and ACX6

DIOPT Version :9

Sequence 1:NP_611264.2 Gene:CG5009 / 37028 FlyBaseID:FBgn0027572 Length:669 Species:Drosophila melanogaster
Sequence 2:NP_172120.2 Gene:ACX6 / 837141 AraportID:AT1G06310 Length:675 Species:Arabidopsis thaliana


Alignment Length:652 Identity:168/652 - (25%)
Similarity:276/652 - (42%) Gaps:116/652 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 FNPREFSVLWAGGE--------ERFKEKK--ALEKLF--LEDPALQDDLPISYLS----HKELYE 67
            |||::     .||:        :..::::  :::::|  ||....|     .:|:    ..||.:
plant    78 FNPKQ-----RGGQIFVSPDYNQTMEQQRQISMKRIFYLLEKGVFQ-----GWLTETGPEAELKK 132

  Fly    68 HSLRKACIIGEKIRKLRADGEDGVDTYNALLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTMDQ 132
            .:|.:.|.|                 |:..|...||           :|::::...:...||...
plant   133 FALYEVCGI-----------------YDYSLSAKLG-----------VHFLLWGNAVKFFGTKRH 169

  Fly   133 QVEWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTA 197
            ..:||....|..:.|.:|.|||||||.:||:||...||.:|:|||||||..||.|:|.|...:.|
plant   170 HEKWLKDTEDYVVKGCFAMTELGHGTNVRGIETVTTYDPTTEEFVINTPCESAQKYWIGEAANHA 234

  Fly   198 NHAVVVAQLYTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKNVRVPL 262
            |||:|::||...|..:|:..||.|:||.|.: ..|.:.|.|.|.|:|:.||:||.:...|:|:|.
plant   235 NHAIVISQLSMNGTNQGIHVFIAQIRDHDGN-TCPNVRIADCGHKIGLNGVDNGRIWFDNLRIPR 298

  Fly   263 NNMLMKNQQVLPDGTYVAP-KNSVLTYGTMMFV----RCALIRDTAQSLAKASTIATRYSAVRRQ 322
            .|:|.....||.||.||:. |:....:|..:..    |..:......|......:|.|||..||.
plant   299 ENLLNSVADVLADGKYVSSIKDPDQRFGAFLAPLTSGRVTIASSAIYSAKLGLAVAIRYSLSRRA 363

  Fly   323 SPIDPNQPEPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIEQGNLDRLPE----M 383
            ..:..|.||..::|:.:.|.:|.|.:||........:.:..:|           :.|.||    :
plant   364 FSVAANGPEVLLLDYPSHQRRLLPLLAKTYAMSFAVNDLKMIY-----------VKRTPETNKAI 417

  Fly   384 HALSCCLKAICSADAAAGVETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTARYL 448
            |.:|...||:.:......::.||.:.||.|....:....:.|......|:||:|.|::...::.|
plant   418 HVVSSGFKAVLTWHNMRTLQECREAVGGQGLKTENRVGHLKGEYDVQTTFEGDNNVLMQLVSKAL 482

  Fly   449 VKVYGQALNGEKLVPTVSYISDAINQTKFVNFDGSLRSIVKAFQFVAANKTRIAYEQIELRRKQG 513
            ...|.......|  |......:.:|..:.|.......|.::..||   .|:.....:.:|..:  
plant   483 FAEYVSCKKRNK--PFKGLGLEHMNSPRPVLPTQLTSSTLRCSQF---QKSVFCLRERDLLER-- 540

  Fly   514 YGTEVAANLCGTFLTAAADLHGRA------FL--------AQTAYTELLALSREVSPE------- 557
                        |.:..|:|.||.      ||        ...|:||...|...:..|       
plant   541 ------------FTSEVAELQGRGESREFLFLLNHQLSEDLSKAFTEKAILQTVLDAEAKLPPGS 593

  Fly   558 LAEVLKVVLELYLVDACLNRIGDFLRFIDLTDQDVTKLEVRLENCLKRFRPNAVSLVDSFDLHDR 622
            :.:||.:|..:|.: ..|......||:..|:..:|..:...:.......||:|::||.||.:.|.
plant   594 VKDVLGLVRSMYAL-ISLEEDPSLLRYGHLSRDNVGDVRKEVSKLCGELRPHALALVASFGIPDA 657

  Fly   623 VL 624
            .|
plant   658 FL 659

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5009NP_611264.2 AXO 8..645 CDD:173839 168/652 (26%)
PLN02443 10..669 CDD:178062 168/652 (26%)
ACX6NP_172120.2 PLN02312 1..675 CDD:215178 168/652 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1960
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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