DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5009 and ACADSB

DIOPT Version :9

Sequence 1:	NP_611264.2	Gene:	CG5009 / 37028	FlyBaseID:	FBgn0027572	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001600.1	Gene:	ACADSB / 36	HGNCID:	91	Length:	432	Species:	Homo sapiens

Alignment Length:	269	Identity:	65/269 - (24%)
Similarity:	111/269 - (41%)	Gaps:	64/269 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLQKERSTATFNPREFSVLWAGGEERFK-EKKALEKLFLE-------DPALQDDLPISYLSHKEL 65
            ::..:.|...|...:.:.|.:..:|..| ||..::.||.:       ||. ......|:||
Human    61 EMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPE-YGGTGASFLS---- 120

  Fly    66 YEHSLRKACIIGEKIRKLRADGEDGVDTYNALLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTM 130
                   ..::.|::.|:.|......:..|.|:            |.|          |...||.
Human   121 -------TVLVIEELAKVDASVAVFCEIQNTLI------------NTL----------IRKHGTE 156

  Fly   131 DQQVEWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGH 195
            :|:..:|.:. ..|.:|::..:|.|.|:....|:||||.:.  ..:|:|     ..|.|..
Human   157 EQKATYLPQL-TTEKVGSFCLSEAGAGSDSFALKTRADKEG--DYYVLN-----GSKMWIS---- 209

  Fly   196 TANHA---VVVAQLYTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKN 257
            :|.||   :|:|.:.....::|:..|:|   |.||    ||:.||....|||::..:...|..:|
Human   210 SAEHAGLFLVMANVDPTIGYKGITSFLV---DRDT----PGLHIGKPENKLGLRASSTCPLTFEN 267

  Fly   258 VRVPLNNML 266
            |:||..|:|
Human   268 VKVPEANIL 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	65/269 (24%)
CG5009	NP_611264.2	PLN02443	10..669	CDD:178062	65/268 (24%)
ACADSB	NP_001600.1	CaiA	57..428	CDD:224871	65/269 (24%)
		SCAD_SBCAD	59..430	CDD:173847	65/269 (24%)
		Substrate binding. /evidence=ECO:0000269\|Ref.15	291..294
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810