DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5009 and CG17544

DIOPT Version :9

Sequence 1:	NP_611264.2	Gene:	CG5009 / 37028	FlyBaseID:	FBgn0027572	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001163015.1	Gene:	CG17544 / 35213	FlyBaseID:	FBgn0032775	Length:	693	Species:	Drosophila melanogaster

Alignment Length:	732	Identity:	200/732 - (27%)
Similarity:	318/732 - (43%)	Gaps:	136/732 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPAKPVNPDLQKERSTATFNPREFSVLWAGGEERFKEKKALEKLFLEDPALQDDLPISY-----L 60
            :|..|....|...|..|.|:       |          |.|..:|.::..|:    |.|     |
  Fly     9 IPDLPSGGPLAVYRKRANFD-------W----------KRLRLIFEKEQGLR----IKYKVWRRL 52

  Fly    61 SHKELYEHSLR--------KAC-----------IIGEKIRKLRADGEDGVDTY-NALLGGSLGSA 105
            .:..|:.|..|        :.|           ::.::|..|....:.....| |..|.....|.
  Fly    53 ENDPLFAHPSRTLPMDEQKRLCAMQVNRMKHLDLVPKEIESLSFSAKTKYLMYINEALACYSPSL 117

  Fly   106 ILKEGNPLALHYVMFVPTIMGQGTMDQQVEWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYD 170
            .:|    :||...:|...|...||...| :::..||:.|:|...|.|||.||:..:.:.|.|.||
  Fly   118 SVK----IALGVGLFNNAIRAMGTEKHQ-KYIEAAWNREVITCLAITELSHGSNTKSIRTTATYD 177

  Fly   171 ASTQEFVINTPSLSAYKWWPGGLGHTANHAVVVAQLYT-KGEFRGLAPFIVQLRDSDTHRPMPGI 234
            .:|||||||||...|.|.|.|.||.||..|:..|.||| .|:..||..|::.:||..|....||:
  Fly   178 PTTQEFVINTPDFEAAKCWVGNLGKTATVAMTFANLYTADGQNHGLHGFLIPIRDPKTLLSYPGV 242

  Fly   235 DIGDIGTKLGMKGVNNGYLGLKNVRVPLNNMLMKNQQVLPDGTYVAPKNSVLTY-GTMMFV---- 294
            .:||||.|.|:.|::||::...|.|:|.:|:|.:...|.|:|.|    .||.|. |.::..
  Fly   243 LVGDIGEKCGLNGIDNGFVVFTNYRIPRDNLLNRTSDVTPEGVY----ESVFTEPGKVLGAALES 303

  Fly   295 ----RCALIRDTAQSLAKASTIATRYSAVRRQSPIDPNQPEPQIMDHTTQQLKLFPQIAKAIVFK 355
                |..:::::|.:|..|:.||.||||||:|...:.:..|..|:::...|.::||.:|.|.|.|
  Fly   304 FSAGRIGIMQESANTLCSAAVIAVRYSAVRKQFGPERHGEEMAILEYQLHQYRIFPYLAAACVQK 368

  Fly   356 TTGDGIWNMYN--VISGEIEQGNLDRL----PEMHALSCCLKAICSADAAAGVETCRLSCGGHGY 414
            ...:.:.:.|.  :...:.:....|.|    .|:|||....|.:.:..|...::..|.:||||||
  Fly   369 IATEELTSTYMEIIARSQADSNGFDVLTQNAAEIHALISSSKPLITWAARDAIQEAREACGGHGY 433

  Fly   415 MDCSNFPTIYGMTTAVCTYEGENTVMLLQTARYLVKVYGQALNGEKLVPTVSYISDAINQTKFVN 479
            :..:....:......:|||||:|.|:..|.:.:|::.:           :...:...|...||:
  Fly   434 LQAAKLGQMRTDHDPLCTYEGDNNVLGQQASNWLLRQW-----------SAKELETPIGSVKFL- 486

  Fly   480 FDGSLRSIVKAFQFVA-ANKTRIAYEQIELRRKQGYGTEVAANLCGTFLTAAADLHGR------A 537
               ..||.:.|..:.: |.||.||..|..||..:..       ||.......|.:.|:      .
  Fly   487 ---ERRSELLALNYASLAQKTPIASWQFSLRCYEWL-------LCHLMAKTTAHIEGQLAAGSSK 541

  Fly   538 FLAQT------------AYTELLALSR--------EVSPELAEVLKVVLELY---LVDACLNR-- 577
            |.|:.            ||.|..||:|        .|....|.||:::.::|   |::..:..
  Fly   542 FEARNNSQVAGARELSLAYAEYYALTRYVDHVSTLTVEAPYASVLRLLFDVYAMWLLEKHMTTFY 606

  Fly   578 IGDFLRFIDLTDQDVTKLEVRLENCLKRFRPNAVSLVDSFDLHDRVLDSALGAYDGNVYEHIFES 642
            :|.|....|.:   ....::.|::||| .:..|||:.|:....|..|:|.:...||.:||::...
  Fly   607 VGGFAAGRDFS---AAVRQLLLDSCLK-LKDVAVSVADAISPPDFALNSVIARADGLLYENLQNE 667

  Fly   643 TKKNPLNKEPVNGAFHK 659
            ...|       .|||.:
  Fly   668 FMTN-------EGAFQR 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	194/709 (27%)
CG5009	NP_611264.2	PLN02443	10..669	CDD:178062	198/723 (27%)
CG17544	NP_001163015.1	AXO	16..670	CDD:173839	194/709 (27%)
CG17544	NP_001163015.1	PLN02443	18..687	CDD:178062	198/723 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910