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Protein Alignment CG5009 and GCDH

DIOPT Version :9

Sequence 1:	NP_611264.2	Gene:	CG5009 / 37028	FlyBaseID:	FBgn0027572	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_000150.1	Gene:	GCDH / 2639	HGNCID:	4189	Length:	438	Species:	Homo sapiens

Alignment Length:	427	Identity:	92/427 - (21%)
Similarity:	154/427 - (36%)	Gaps:	119/427 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 HKELYEHSLRKACIIGEKIRKLRADGEDGVDTYNAL------LGGSLGSAILKEGNPLALHYVMF 120
            |:|:.. .:.:..::|..|:.....|...| .|..|      :.....||:..:.: |.:|
Human    93 HREIIS-EMGELGVLGPTIKGYGCAGVSSV-AYGLLARELERVDSGYRSAMSVQSS-LVMH---- 150

  Fly   121 VPTIMGQGTMDQQVEWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSA 185
              .|...|:.:|:.::|.:....|::|.:..||...|:....:||||.|::|.:.:.:|     .
Human   151 --PIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLN-----G 208

  Fly   186 YKWWPGGLGHTANHAVVVAQLYTKGEFRGLAPFIVQLRDSD-------THRPMPGIDIGDIGTKL 243
            .|.|                 .|......|  |:|..|..|       ..:.|.|:....|..|.
Human   209 TKTW-----------------ITNSPMADL--FVVWARCEDGCIRGFLLEKGMRGLSAPRIQGKF 254

  Fly   244 GMKGVNNGYLGLKNVRVPLNNMLMKNQQVLPDGTYVAPKNSVL--TYGTMMFVRCALIRDTAQSL 306
            .::....|.:.:..|.||..|:|              |..|.|  .:|.:...|..:    |..:
Human   255 SLRASATGMIIMDGVEVPEENVL--------------PGASSLGGPFGCLNNARYGI----AWGV 301

  Fly   307 AKASTI----ATRYSAVRRQ--SPIDPNQPEPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMY 365
            ..||..    |.:|:..|.|  .|:..||                      ::.|...|.:..:.
Human   302 LGASEFCLHTARQYALDRMQFGVPLARNQ----------------------LIQKKLADMLTEIT 344

  Fly   366 NVISGEIEQGNL---DR-LPEMHAL---SCCLKAICSADAAAGVETCRLSCGGHGYMDCSNFPTI 423
            ..:...::.|.|   |: .|||.:|   :.|.||:..|..|      |...||:|..|  .:..|
Human   345 LGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKALDIARQA------RDMLGGNGISD--EYHVI 401

  Fly   424 -YGMT-TAVCTYEGENTVMLLQTARYLVKVYGQALNG 458
             :.|. .||.||||.:.:..|        :.|:|:.|
Human   402 RHAMNLEAVNTYEGTHDIHAL--------ILGRAITG 430

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.