Protein Alignment CG5009 and Acox2

DIOPT Version :9

• Sequence 1: NP_611264.2
• Gene: CG5009 / 37028
• FlyBaseID: FBgn0027572
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_665713.2
• Gene: Acox2 / 252898
• RGDID: 628684
• Length: 681
• Species: Rattus norvegicus
• Alignment Length: 689
• Identity: 246/689 - (35%)
• Similarity: 360/689 - (52%)
• Gaps: 61/689 - (8%)

  Fly     6 VNPDLQKERSTATFNPREFSVLWAGGEERFKEKKALEKLFLEDPALQDDLPISYLSHKELYEHSL 70
            |:||:..||.:.:|:....:.:..||......::.:|.:...||.. :...:.:::.:||||.::
  Rat    18 VHPDIDSERHSPSFSVERLTNILDGGLPNTVLRRKVESIIQSDPVF-NLKKLYFMTREELYEDAI 81

  Fly    71 RKACIIGEKIRKLRADGEDGVDTY--NALLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTMDQQ 133
            :|...: ||:.......|||.:..  |.:|.|::.         |:||.|. :..|...|:.:|.
  Rat    82 QKRFHL-EKLAWSLGWSEDGPERIYANRVLDGNVN---------LSLHGVA-MNAIRSLGSDEQI 135

  Fly   134 VEWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTAN 198
            .:|.....:.:||.|||||||||||:|:||||.|.||.:.|||||::|::::.|||||.||.:..
  Rat   136 AKWGQLCKNFQIITTYAQTELGHGTYLQGLETEATYDEARQEFVIHSPTMTSTKWWPGDLGWSVT 200

  Fly   199 HAVVVAQLYTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKNVRVPLN 263
            ||||:|||...|...|:..|||.:|..:.|.|:|||.:||||.|:|::.::||:|.|.:||||..
  Rat   201 HAVVLAQLTCLGVRHGMHAFIVPIRSLEDHTPLPGITVGDIGPKMGLEHIDNGFLQLNHVRVPRE 265

  Fly   264 NMLMKNQQVLPDGTYVAPKNSVLTYGTMMFVRCALI-RDTAQSLAKASTIATRYSAVRRQSPIDP 327
            |||.:..:|||||||.........|..|:..|..|: :....||.||..||||||.:|.||.:.|
  Rat   266 NMLSRFAEVLPDGTYQRLGTPQSNYLGMLVTRVQLLCKGILPSLQKACIIATRYSVIRHQSRLRP 330

  Fly   328 NQPEPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIEQGNLDRLPEMHALSCCLKA 392
            :.||.:|:::.|||.||.||:|.:..|..|...:...::.....|.:.:...|||:||||..:||
  Rat   331 SDPEAKILEYQTQQQKLLPQLAVSYAFHFTATSLSEFFHSSYSAILKRDFSLLPELHALSTGMKA 395

  Fly   393 ICSADAAAGVETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTARYLVKVYGQA-- 455
            ..:...|.|.|.||.:||||||...|..||:....||.|||||||||:.||.||:|:|.|.||
  Rat   396 TFADFCAQGAEICRRACGGHGYSKLSGLPTLVARATASCTYEGENTVLYLQVARFLMKSYLQAQA 460

  Fly   456 ---LNGEKLVP-TVSYISD-----AINQTKFVNFDGSLRSIVKAFQFVAANKTRIAYEQIELRRK 511
               ...:|.:| :|.||:.     ...||            ...|:......|..||....|.|.
  Rat   461 SPGATPQKPLPQSVMYIATQRPARCSAQT------------AADFRCPDVYTTAWAYVSTRLIRD 513

  Fly   512 QGYGTEVAANLCGTFLTAAADLHGR-------AFLAQTAYTELLALSR--------EVSPELAEV 561
            ..:.|:       |.:.:..|.|..       ...|..||...:.:..        :..||:..|
  Rat   514 AAHRTQ-------TLMKSGVDQHDAWNQTTVIHLQAAKAYCYFITVKNFKEAVEKLDKEPEIQRV 571

  Fly   562 LKVVLELYLVDACLNRIGDFLRFIDLTDQDVTKLEVRLENCLKRFRPNAVSLVDSFDLHDRVLDS 626
            |:.:.:||.:...|...||||....|:...|........:.|...|.:|:.|.|:||..|..|:|
  Rat   572 LQRLCDLYALHGVLTNSGDFLHDGFLSGAQVDMAREAFLDLLPLIRKDAILLTDAFDFSDHCLNS 636

  Fly   627 ALGAYDGNVYEHIFESTKKNPLNKEPVNGAFHKYLKPFM 665
            |||.|||:|||.:||..:|:|.|.:. |.|:.||::|.|
  Rat   637 ALGCYDGHVYERLFEWAQKSPANTQE-NPAYKKYIRPLM 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	236/665 (35%)
		PLN02443	10..669	CDD:178062	243/685 (35%)
Acox2	NP_665713.2	AXO	20..655	CDD:173839	236/665 (35%)
		Microbody targeting signal. /evidence=ECO:0000255	679..681

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348955
Domainoid	1	1.000	108	1.000	Domainoid score	I6284
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54939
OrthoDB	1	1.010	-	-		D203634at33208
OrthoFinder	1	1.000	-	-		FOG0001030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100457
Panther	1	1.100	-	-	O	PTHR10909
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X618
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.760