Protein Alignment ACOX1 and acox-3

DIOPT Version :10

• Sequence 1: NP_611264.2
• Gene: ACOX1 / 37028
• FlyBaseID: FBgn0027572
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_500943.1
• Gene: acox-3 / 177386
• WormBaseID: WBGene00019060
• Length: 667
• Species: Caenorhabditis elegans
• Alignment Length: 689
• Identity: 203/689 - (29%)
• Similarity: 327/689 - (47%)
• Gaps: 88/689 - (12%)

  Fly     8 PDLQKERSTATFNPREFSVLWAGGEERFKEKKALEKLFLEDPALQDDLPISYLSHKELYEHSLRK 72
            |.:.|.|..|||:.::.... ..|||..:.|..:......:|....|..:  ||.:|..|
 Worm     4 PLIDKYRKMATFDWKKLKAA-VEGEEHVRLKSEVVAKMKSEPVFHRDYRV--LSREEQRE----- 60

  Fly    73 ACIIGEKIRK-----LRADGEDGVDTYNALLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTMDQ 132
              ::.::.:|     |..|....::.::||. .:|.:........|.||..:|...:...|| |:
 Worm    61 --VVHQRWKKIVEWGLFKDPYSDLENFHALT-ETLEAYDQGTSARLFLHGNVFGAAVKSMGT-DR 121

  Fly   133 QVEWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTA 197
            ..:.:.|..:.||:|.:..||:|||:....::|.|.:|  ..|.|.||||:||.|.|.|.|.|:|
 Worm   122 HKDLIQKTENNEIVGAFCLTEVGHGSNTAEIQTTATFD--NGELVFNTPSVSAIKCWAGNLAHSA 184

  Fly   198 NHAVVVAQLYTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLG-MKGVNNGYLGLKNVRVP 261
            .|.||.|||:.:|:..|...|::|:|...|.:.:|||.|||:|:|.| .:||.||::..||.|.|
 Worm   185 THVVVYAQLHVEGKNEGFHGFVIQVRCPRTFQTLPGITIGDMGSKPGCWQGVENGWMEFKNHRAP 249

  Fly   262 LNNMLMKNQQVLPDGTYV-----APKNSVLTYGTMMFVRCALIRDTAQSLAKASTIATRYSAVRR 321
            |:.:|.|...:.|||.||     |.:...::.||:...|..:|.....:...|||||.|||..||
 Worm   250 LSALLNKGCDITPDGKYVTSFKSASEKQSVSLGTLSVGRLGIIAKGMMACTFASTIAIRYSVARR 314

  Fly   322 Q-SPIDPNQPEPQIMDHTTQQLKLFPQIAKAI---VF--KTTGDGIWNMYNVISGEIEQGNLDRL 380
            | .|:...:.|..::::..||.:|||.::.||   :|  |..|.....|..||.||......:..
 Worm   315 QFGPVKGAENEIPVLEYPLQQYRLFPYLSAAICIRIFQKKFVGHFTEYMMRVIMGEKSDELSEFS 379

  Fly   381 PEMHALSCCLKAICSADAAAGVETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTA 445
            .|:||||...|.:.:......:...|.:||||||:..|...|:........|:||||.::|.||:
 Worm   380 KEVHALSSGAKPVATWLGVESLGEARKACGGHGYLQMSRLNTLRDDNDPSQTFEGENFMILQQTS 444

  Fly   446 RYLVKVYGQALN-G--EKLVPTVSYISDAINQTKFVNFDGS-LRSIVKAFQFVAANKTRIAYEQI 506
            ..|:   |:|.: |  |..:.|:|:::.  ..:||.::..: :..::.|:::       :.|..:
 Worm   445 NILL---GKAQSIGSIETPMSTMSFLNQ--KPSKFSSWSSNPVNDVLSAYRY-------LTYHLL 497

  Fly   507 ELRRKQGYGTEVAANLCGTF-LTAAADLHGRAFLAQTAYTELLAL-----------SREVSPELA 559
            :....:.|..:.:..  .:| :.....:| ||.....||||...:           .:.|.|.|.
 Worm   498 QTTSAEAYRLKASGK--NSFEVRNEIQIH-RAVNLSVAYTEHTMIHWVQQFLKEIEDQSVKPVLQ 559

  Fly   560 EVLKVVLELYLVDACL-----------NRIGDFLRFIDLTDQDVTKLEVRLENCLKRFRPNAVSL 613
            :||. :..|:|::..|           .:.|:.||             .:|...:...:|.|::|
 Worm   560 KVLN-LFSLFLLERHLATLYITGYASGGKFGEDLR-------------EKLRLAVAELKPEAIAL 610

  Fly   614 VDSFDLHDRVLDSALGAYDGNVYEHIFESTKKNPLNKEP 652
            |||....|.:|.|||||.||..||||.|..:|. .|::|
 Worm   611 VDSIAPDDFILHSALGASDGKAYEHIMEEFRKY-TNEQP 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACOX1	NP_611264.2	AXO	8..645	CDD:173839	200/680 (29%)
acox-3	NP_500943.1	AXO	4..642	CDD:173839	200/680 (29%)