Protein Alignment CG5009 and acox-1.2

DIOPT Version :9

• Sequence 1: NP_611264.2
• Gene: CG5009 / 37028
• FlyBaseID: FBgn0027572
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_493262.2
• Gene: acox-1.2 / 173163
• WormBaseID: WBGene00008565
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 267/672 - (39%)
• Similarity: 388/672 - (57%)
• Gaps: 30/672 - (4%)

  Fly     7 NPDLQKERSTATFNPREFSVLWAGGEERFKEKKALEKLFLEDPALQDDLPISYLSHKELYEHSLR 71
            ||:|.:||..|||:..:.:.:..|.||..:.::.:.....:.|.|.|..|..:|:.:|......|
 Worm    11 NPELLEERRMATFDTDKMAAVIYGSEEFARRRREITDAVSKIPELADIKPYPFLTREEKVTEGTR 75

  Fly    72 KACIIGEKIRKL--RADGEDGVDTYNALLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTMDQQV 134
            |..|:.:.:.:|  |.:.|:.:..:..::|        .||:|.|||..:|:||:..|.:.:||.
 Worm    76 KISILTKYLNQLIDRDNEEESLHLHREVIG--------YEGHPFALHDALFIPTLQSQASDEQQE 132

  Fly   135 EWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTANH 199
            :||.:|...||||.|||||||||:.||.|||.|.||.::||||::||:.:|.|||||.||.:.|:
 Worm   133 KWLERARRREIIGCYAQTELGHGSNLRNLETTAVYDIASQEFVLHTPTTTALKWWPGALGKSCNY 197

  Fly   200 AVVVAQLYTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKNVRVPLNN 264
            |:|||:|..|....|...|:|||||..||.|:.|:.:||||.|:.....:||||||.|:|||..|
 Worm   198 ALVVAELIIKRNNYGPHFFMVQLRDEKTHIPLKGVTVGDIGPKMNFNAADNGYLGLNNLRVPRTN 262

  Fly   265 MLMKNQQVLPDGTYVAPKNSVLTYGTMMFVRCALIRDTAQSLAKASTIATRYSAVRRQSPIDPNQ 329
            :||::.:|..|||||.|.::.:.|..|:.:|..:..:....||.|.|||.||||||||..:|..|
 Worm   263 LLMRHCKVEADGTYVKPPHAKIGYSGMVKIRSQMAMEQGLFLAHALTIAARYSAVRRQGHLDDKQ 327

  Fly   330 PEPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIEQGNLDRLPEMHALSCCLKAIC 394
            .|.:::|:.|||.:|||.:|:|..|..||....::|:.:..:::.||...:.::|||:..||::.
 Worm   328 VEVKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVV 392

  Fly   395 SADAAAGVETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTARYLVKVYG--QALN 457
            :.:...|:|..|::||||||...|....:||:....|||||||.|||||.||||||...  :|..
 Worm   393 AHETGEGIEQARMACGGHGYSMASYISVVYGIAIGGCTYEGENMVMLLQLARYLVKSVELIKAGK 457

  Fly   458 GEKLVPTVSYISDAINQTKFVNFDGSLRSIVKAFQFVAANKTRIAYEQIELRRKQGYGTEVAANL 522
            .:||.|..||::|..::|...    ||...||.|:.:|..:...|.|:.....:.|...|||.|.
 Worm   458 AKKLGPVASYLADKSDETDLT----SLNGYVKMFENMARRQAWKATEKFLKLMESGESREVAWNK 518

  Fly   523 CGTFLTAAADLHGRAFLAQTAYTELLALSREVSP----ELAEVLKVVLELYLVDACLNRIGDFLR 583
            ....||.|:.||.|.|:.:       |..|.||.    .:.|||..:|.|::....|:.....|.
 Worm   519 SAVELTRASRLHTRLFIIE-------AFMRRVSRIEDIPVKEVLTDLLHLHVNYELLDVATYALE 576

  Fly   584 FIDLTDQDVTKLEVRLENCLKRFRPNAVSLVDSFDLHDRVLDSALGAYDGNVYEHIFESTKKNPL 648
            |:..|..|..:.::.|  .|::.|||||||||||.:.|..|.|.||..||:|||::|:..|.:||
 Worm   577 FMSFTQLDYVRDQLYL--YLEKIRPNAVSLVDSFQISDMQLRSVLGRRDGHVYENLFKWAKSSPL 639

  Fly   649 NKEPVNGAFHKYLKPFM-KAHL 669
            |...|..:..|||||.| ||.|
 Worm   640 NNADVLPSVEKYLKPMMEKAKL 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	252/644 (39%)
		PLN02443	10..669	CDD:178062	264/667 (40%)
acox-1.2	NP_493262.2	ACAD	12..635	CDD:299127	252/643 (39%)
		PLN02443	14..658	CDD:178062	262/664 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163715
Domainoid	1	1.000	206	1.000	Domainoid score	I1698
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38299
Inparanoid	1	1.050	482	1.000	Inparanoid score	I803
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54939
OrthoDB	1	1.010	-	-		D203634at33208
OrthoFinder	1	1.000	-	-		FOG0001030
OrthoInspector	1	1.000	-	-		mtm4727
orthoMCL	1	0.900	-	-		OOG6_100457
Panther	1	1.100	-	-	O	PTHR10909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X618
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770