DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5009 and AgaP_AGAP008769

DIOPT Version :9

Sequence 1:	NP_611264.2	Gene:	CG5009 / 37028	FlyBaseID:	FBgn0027572	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_314893.4	Gene:	AgaP_AGAP008769 / 1275626	VectorBaseID:	AGAP008769	Length:	624	Species:	Anopheles gambiae

Alignment Length:	533	Identity:	113/533 - (21%)
Similarity:	190/533 - (35%)	Gaps:	141/533 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 DTYNALLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTMDQQVEWLSKAWDCEIIGTYAQTELGH 156
            :|..|.:|..:|:|.|........|..:....::..||.:|:.::|.:......|..:..||...
Mosquito   127 NTGYARMGELVGAADLGLAVVFGAHQSIGWKGVLLYGTEEQKRKYLPQVVTGGTIACFCLTEPSS 191

  Fly   157 GTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTANHAVVVAQLYTKGEFRG-----LA 216
            |:....:.:||...|....:|:|     ..|.|..| |..|:...|.||........|     :.
Mosquito   192 GSDAGSIRSRAVKSADGSHYVLN-----GSKIWISG-GGLADIFTVFAQTEVTDPKTGQKKDKVT 250

  Fly   217 PFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKNVRVPLNNML-------------MK 268
            .|||:       |...|:..|....|:|:|..|...:...:|::|..|:|             :.
Mosquito   251 AFIVE-------RGFGGVTSGPPEDKMGIKCSNTAEVYFDDVKIPAENVLGGEGNGFKVAMNILN 308

  Fly   269 NQQVLPDGTYVAPKNSVLTYGTMMFVRCALIRDTAQSLAKASTIATRYSAVRRQSPIDPNQPEPQ 333
            |.:....||..         |||           |..:.||:..||        :.:...|   :
Mosquito   309 NGRFGMSGTLA---------GTM-----------AHCIRKAAEHAT--------TRVQFGQ---K 342

  Fly   334 IMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIEQGNLDRLPEMHALSCCLKAICSADA 398
            |.:....|.||........|.::.|       .:|||.::.|:.|     :.|...:..|.|::|
Mosquito   343 IENFGNVQEKLARMAMHQYVSQSMG-------YMISGNMDAGHTD-----YHLEAAISKIFSSEA 395

  Fly   399 AAGV--ETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTARYLVKVYGQALNGEKL 461
            |..|  |..:: .||:|:|..|..............:||.|.::     |..|.:.|
Mosquito   396 AWYVCDEAIQI-LGGNGFMKSSGLEKFLRDIRIYRIFEGANDIL-----RLFVTLTG-------- 446

  Fly   462 VPTVSYISDAINQTKFVNFDGS-LRSIVKAFQFVAANKTRIAYEQIELR--RKQGY-GTEV---- 518
                            :.:.|| |:.:.:||:...|| ..:.:::...|  |..|| ||::
Mosquito   447 ----------------IQYAGSHLKELQRAFKNPTAN-LGLIFKEGSRRAVRSIGYGGTDLSTFV 494

  Fly   519 ------AANLCGTFL-----TAAADL--HGRAFLAQTAYTELLALSREVSPELAEVLKVVLELYL 570
                  :|.||...:     |..|.|  ||:..:.|......||.|             .:::|.
Mosquito   495 VDPLKESAALCADSIDRFSKTIEALLIKHGKGIVDQQFLLIRLADS-------------AIDIYG 546

  Fly   571 VDACLNRIGDFLR 583
            :...|:|....:|
Mosquito   547 MSCVLSRASKAVR 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	113/533 (21%)
CG5009	NP_611264.2	PLN02443	10..669	CDD:178062	113/533 (21%)
AgaP_AGAP008769	XP_314893.4	VLCAD	41..451	CDD:173850	84/409 (21%)
AgaP_AGAP008769	XP_314893.4	CaiA	63..442	CDD:224871	82/376 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810