DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5009 and AgaP_AGAP008602

DIOPT Version :9

Sequence 1:	NP_611264.2	Gene:	CG5009 / 37028	FlyBaseID:	FBgn0027572	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_314701.4	Gene:	AgaP_AGAP008602 / 1275454	VectorBaseID:	AGAP008602	Length:	417	Species:	Anopheles gambiae

Alignment Length:	474	Identity:	106/474 - (22%)
Similarity:	181/474 - (38%)	Gaps:	115/474 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ERFKEKKALEKLFLEDPALQDDLPISYLSHKELYEHSLRKACIIGEK--------IRKLRADGED 89
            |.|..:.||.:.|......::...:..|. ::..|..|:.|....::        |.||...|..
Mosquito    20 EAFNSRCALSRSFSVCELSKEHQQVQQLC-RQFSERELKPAASAIDRNGTFPEQHIAKLAELGLM 83

  Fly    90 GVDTYNALLGGS----LGSAILKE---------GNPLALHYVMFVPTIMGQGTMDQQVEWLSKAW 141
            .| |...|.|||    |..:::.|         |:.:::|..::...:...||.||:..:.:| :
Mosquito    84 RV-TVAPLYGGSGLDMLSLSLVVEELSRGCGSTGSIVSIHNCLYANLLHRLGTDDQRARFFNK-Y 146

  Fly   142 DCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTANHAVVVAQL 206
            :.:.||.:|.:|.|.|:.:..:.|||..||.....:..|.:     |...|:...|  |:|.|.:
Mosquito   147 ESKTIGAFALSEAGAGSDVAAMTTRATRDADGSWILNGTKA-----WVTSGIESVA--AIVFATV 204

  Fly   207 YTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKNVRVPLNNML----- 266
            ....:::|:..|:|.. ||..   :.|:..|....|||::|.:...|.|:|||||..|:|
Mosquito   205 DPALKYKGITAFLVDF-DSGA---LAGVHRGRPEDKLGIRGTSTCDLMLENVRVPEANVLGTVGS 265

  Fly   267 -MKNQQVLPDGTYVAPKNSVLTYGTMMFVRCALIRDTAQSLAKASTIATRYSAVRRQSPIDPNQP 330
             |:......|...:...:..:..|     :.||  :||...||..|       ....:.||....
Mosquito   266 GMRIAMEQLDRARIGIASQAIGIG-----QAAL--ETAVEYAKQRT-------AFGGTLIDLPAV 316

  Fly   331 EPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIEQGNLDRLPEMHALSCC--LKAI 393
            ..:|.:..|:.     ::|:.:|.|.            :|||::|       :.|...|  .|.|
Mosquito   317 RTRIAEMGTRL-----EMARLLVRKA------------AGEIDRG-------LRATKACSMAKWI 357

  Fly   394 CSADAAAGVETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTARY-----LVKVYG 453
            ....|......|:...||.||                        |..|...||     :.::||
Mosquito   358 AGETATYAAHGCQQILGGMGY------------------------VKSLPAERYYRDARITEIYG 398

  Fly   454 QALNGEKLVPTVSYISDAI 472
            ...:.:|.:     ::|.|
Mosquito   399 GVTDVQKAI-----VADQI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	106/474 (22%)
CG5009	NP_611264.2	PLN02443	10..669	CDD:178062	106/474 (22%)
AgaP_AGAP008602	XP_314701.4	CaiA	36..416	CDD:224871	101/458 (22%)
AgaP_AGAP008602	XP_314701.4	ACAD	40..414	CDD:299127	101/454 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810