DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5009 and AgaP_AGAP011215

DIOPT Version :9

Sequence 1:	NP_611264.2	Gene:	CG5009 / 37028	FlyBaseID:	FBgn0027572	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_309430.4	Gene:	AgaP_AGAP011215 / 1270711	VectorBaseID:	AGAP011215	Length:	708	Species:	Anopheles gambiae

Alignment Length:	621	Identity:	180/621 - (28%)
Similarity:	267/621 - (42%)	Gaps:	122/621 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LALHYVMFVPTIM----GQGTMDQQVEWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDAST 173
            |.::|:.|...|.    ..|.:...:|   :|....|.|::|.||:||||..|.:.|||.||.:.
Mosquito   135 LTVNYLFFTGAIRMFDEPGGRLAHVIE---QAEAGHIAGSFALTEVGHGTNARAIRTRATYDPAH 196

  Fly   174 QEFVINTPSLSAYKWWPGGLGHTANHAVVVAQLYT-KGEFRGLAPFIVQLRDSDTHRPMPGIDIG 237
            :|||:.||...|.|.|.|.|..:....:|.||||| .|...|::.|:|.:||..|.:|:||:.:|
Mosquito   197 REFVLETPDFEAAKCWAGNLAKSCTDMIVWAQLYTADGACHGVSAFVVPIRDRYTLQPLPGLLVG 261

  Fly   238 DIGTKLGMKGVNNGYLGLKNVRVPLNNMLMKNQQVLP-DGTYVAPKNS-----VLTYGTMMFVRC 296
            |:|.|.|:.||:||::..:..|:|..|:|.:...|.. .|.:.:...|     .|:.|.::..|.
Mosquito   262 DLGEKAGLNGVDNGFVLFRGYRIPRENLLARFGDVNEVTGRFESTAKSANERFALSMGPLVIGRI 326

  Fly   297 ALIRDTAQSLAKASTIATRYSAVRRQSPIDPNQPEPQIMDHTTQQLKLFPQIAKAIVFK------ 355
            .:...:...||||.||..||||||.|.....:..|..|:::.:||.:|.|.:|..:..|
Mosquito   327 NICTVSQTLLAKALTIGIRYSAVRCQFGPTGDDRELPILEYQSQQYRLLPHLATCVALKLFHRWF 391

  Fly   356 --TTGDGIWNMYNVISGEIEQGNLDRLPEMHALSCCLKAICSADAAAGVETCRLSCGGHGYMDCS 418
              .:||....|......|.|     .|.|:|.::..:|.|||..|..|::..|.:||||||:..:
Mosquito   392 ARVSGDAQVRMLRAAPIESE-----LLLEVHIVASAVKPICSWAARDGIQDAREACGGHGYLRLA 451

  Fly   419 NFPTIYGMTTAVCTYEGENTVMLLQTARYLVKVYGQALNGEKLVPTVSYISDAINQTKFVNFDGS 483
            ....:.....|..||||||.|:|.|.::.||   |....||       |.:.|:....     ||
Mosquito   452 GLADLRVDNDANITYEGENNVLLQQVSQQLV---GIRSKGE-------YGAFALMSPL-----GS 501

  Fly   484 LRSIVKAFQFVAANKTRIAYEQIE--------------------LRRKQG--------------- 513
            :..:.:..|.:.....||..||||                    .||.:|
Mosquito   502 MTFLAEYEQIMQQRLERITVEQIEDPKVILNVLSWLTAYTLEGTYRRAEGLLKRGDSKFDVRNDT 566

  Fly   514 -----------YGTEVAANLCGTFLTAAADLHGRAFLAQTA--YTELLALSREVSPELAEVLKVV 565
                       :|..:..|...|||........|.:|.:.|  |...|.|....:.:.|..| .|
Mosquito   567 QIFYAKDLAIVFGERIIFNAFCTFLDTMEQGPERNYLTRLAQLYGATLLLKHMATLQSAGYL-TV 630

  Fly   566 LELYLVDACLNRIGDFLRFIDLTDQDVTKLEVRLENCLKRFRPNAVSLVDSFDLHDRVLDSALGA 630
            ..|.||...:      ||.:.:..||                  ||:::||....|.||:|.|||
Mosquito   631 DALPLVQESI------LRLLPIVKQD------------------AVAMIDSLAPPDFVLNSPLGA 671

  Fly   631 YDGNVYEHIFESTKKNPLNKEPVNGA---FHKYLKP 663
            .|||||..:    :...:..:.|.|.   :|:.|.|
Mosquito   672 ADGNVYARM----ESELMAGQDVTGRATWWHEILTP 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	175/598 (29%)
CG5009	NP_611264.2	PLN02443	10..669	CDD:178062	180/621 (29%)
AgaP_AGAP011215	XP_309430.4	ACAD	32..685	CDD:299127	175/601 (29%)
AgaP_AGAP011215	XP_309430.4	PLN02443	34..683	CDD:178062	175/599 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810