DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5009 and AgaP_AGAP006780

DIOPT Version :9

Sequence 1:	NP_611264.2	Gene:	CG5009 / 37028	FlyBaseID:	FBgn0027572	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	XP_308965.3	Gene:	AgaP_AGAP006780 / 1270283	VectorBaseID:	AGAP006780	Length:	429	Species:	Anopheles gambiae

Alignment Length:	487	Identity:	112/487 - (22%)
Similarity:	167/487 - (34%)	Gaps:	147/487 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DLQKERSTA-TFNPREFSVL--WAGGEERFKEKKALEKLFLEDPAL-------QDDLPISYLSHK 63
            |.|:.|.|. .|..:|.:.|  ....:..|||.::..:...|...|       ...|..|||.|
Mosquito    52 DQQQLRQTVFNFAQKELAPLAQEIDKQNEFKEMRSFWRKLGEMGVLGVTVKPEYGGLGGSYLDH- 115

  Fly    64 ELYEHSLRKACIIGEKIRKLRADGEDGVDTYNALLGGSLGSAILKEGNPLALHYVMFVPTIMGQG 128
                      ||:.|::.:                  :.||..|..|    .|..:.|..|...|
Mosquito   116 ----------CIVNEELSR------------------ASGSVALSYG----AHSNLCVNQIHRHG 148

  Fly   129 TMDQQVEWLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGL 193
            |.:|:..:|.|....|.||..|.:|.|.|:.:..::.|||...  ..:|:|     ..|:|...
Mosquito   149 TDEQKERYLPKLCSGEHIGALAMSEAGSGSDVVSMKLRADKHG--DYYVLN-----GSKFWITN- 205

  Fly   194 GHTANHAVVVAQLYTKGE-FRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKN 257
            |..|:..|:.|:..|..: ..|:..|||:       |...|...|....|||::|...|.|..::
Mosquito   206 GPVADTYVIYAKTDTSAKPQHGITAFIVE-------RGTAGFTQGPKLDKLGIRGSPTGELIFED 263

  Fly   258 VRVPLNNMLMKNQQVLPDGTYVAPKNSVLTYGTMMFVRCALIRDTAQSLAKASTIATRYSAVRRQ 322
            .:||..|:|    ..|..|.||......|.       |..|.......:..|..:|..|:..|:|
Mosquito   264 AKVPAGNIL----GGLNKGVYVLMSGLDLE-------RLVLAAGPVGLMQAACDVAFEYAHSRKQ 317

  Fly   323 SPIDPNQPEPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIE--QGNL-DRLPEMH 384
                                                      :|...||.:  ||.: |....|:
Mosquito   318 ------------------------------------------FNTRIGEFQLLQGKMADMYTTMN 340

  Fly   385 ALSCCLKAICSA---------DAAAGVETCRLSC-----------GGHGYMDCSNFPTIYGMTTA 429
            |....|.::..|         |.|..:..|....           ||:||:  :::||  |....
Mosquito   341 ACRAYLYSVARACDRGQANPKDCAGVILYCAEKATQVALDAIQILGGNGYI--NDYPT--GRIMR 401

  Fly   430 VC-TYE-GENTVMLLQTARYLVKVYGQALNGE 459
            .| .|| |..|   .:..|.|:   |:|||.|
Mosquito   402 DCKLYEIGAGT---SEIRRMLI---GRALNKE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	112/487 (23%)
CG5009	NP_611264.2	PLN02443	10..669	CDD:178062	111/486 (23%)
AgaP_AGAP006780	XP_308965.3	IVD	48..426	CDD:173845	110/484 (23%)
AgaP_AGAP006780	XP_308965.3	PLN02519	49..427	CDD:215284	111/485 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810