Protein Alignment CG5009 and Acox1

DIOPT Version :9

• Sequence 1: NP_611264.2
• Gene: CG5009 / 37028
• FlyBaseID: FBgn0027572
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001258827.1
• Gene: Acox1 / 11430
• MGIID: 1330812
• Length: 661
• Species: Mus musculus
• Alignment Length: 673
• Identity: 293/673 - (43%)
• Similarity: 420/673 - (62%)
• Gaps: 32/673 - (4%)

  Fly     6 VNPDLQKERSTATFNPREFSVLWAGGEERFKEKKALEKLFLEDPALQDDLPISYLSHKELYEHSL 70
            :||||:|||:.|||||...:.:..|..|..:.::.:|.|.|.||..|.: ..::|:..:.||.::
Mouse     1 MNPDLRKERAAATFNPELITHILDGSPENTRRRREIENLILNDPDFQHE-DYNFLTRSQRYEVAV 64

  Fly    71 RKACIIGEKIRKLRADGEDGVDTYNALLGGSLGSAILKEGNPLALHYVMFVPTIMGQGTMDQQVE 135
            :|:..:.:|:|:......:.:..:..|       .::....|:.|:|.||:||::.|||..||.:
Mouse    65 KKSATMVKKMREFGIADPEEIMWFKKL-------HMVNFVEPVGLNYSMFIPTLLNQGTTAQQEK 122

  Fly   136 WLSKAWDCEIIGTYAQTELGHGTFLRGLETRADYDASTQEFVINTPSLSAYKWWPGGLGHTANHA 200
            |:..:.:.:|||||||||:||||.||||||.|.||..||||::|:|::::.||||||||.|:|||
Mouse   123 WMHPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHA 187

  Fly   201 VVVAQLYTKGEFRGLAPFIVQLRDSDTHRPMPGIDIGDIGTKLGMKGVNNGYLGLKNVRVPLNNM 265
            :|:|||.|:||..||..|:|.:|:..||:|:|||.:||||.|.|.:.::||||.:.|.|:|..||
Mouse   188 IVLAQLITRGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENM 252

  Fly   266 LMKNQQVLPDGTYVAPKNSVLTYGTMMFVRCALIRDTAQSLAKASTIATRYSAVRRQSPIDPNQP 330
            |||..||.||||||.|.::.||||||:|||..|:...||||:||.|||.|||||||||.|..::|
Mouse   253 LMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGSAAQSLSKACTIAIRYSAVRRQSEIKRSEP 317

  Fly   331 EPQIMDHTTQQLKLFPQIAKAIVFKTTGDGIWNMYNVISGEIEQGNLDRLPEMHALSCCLKAICS 395
            ||||:|..|||.||||.:|.|..|...|..|...|..|:..|.||:|..|||:|||:..|||..:
Mouse   318 EPQILDFQTQQYKLFPLLATAYAFHFLGRYIKETYMRINESIGQGDLSELPELHALTAGLKAFTT 382

  Fly   396 ADAAAGVETCRLSCGGHGYMDCSNFPTIYGMTTAVCTYEGENTVMLLQTARYLVKVYGQALNGEK 460
            ..|.||:|.||::||||||...|..|.||...|..||:|||||||:|||||:|:|:|.|..:|:.
Mouse   383 WTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVQSGKL 447

  Fly   461 LVPTVSYISDAINQ----------TKFVNFDGSLRSIVKAFQFVAANKTRIAYEQIELRRKQGYG 515
            :...|||::|..:|          ...|:.: ||.|:.:|::..||....||.:.::.:......
Mouse   448 VGGMVSYLNDLPSQRIQPQQVAVWPTLVDIN-SLDSLTEAYKLRAARLVEIAAKNLQAQVSHRKS 511

  Fly   516 TEVAANLCGTFLTAAADLHGRAFLAQTAYTELLALSREVSPELAE-----VLKVVLELYLVDACL 575
            .|||.||....|..|::.|.. ::....:.:.|       |::.:     ||:.:..||.:....
Mouse   512 KEVAWNLTSVDLVRASEAHCH-YVTVKVFADKL-------PKIQDRAVQAVLRNLCLLYSLYGIS 568

  Fly   576 NRIGDFLRFIDLTDQDVTKLEVRLENCLKRFRPNAVSLVDSFDLHDRVLDSALGAYDGNVYEHIF 640
            .:.||||....:|...::::..|:...|...|||||:|||:||..|..|.|.||.|||||||::|
Mouse   569 QKGGDFLEGNIITGAQMSQVNSRILELLTVTRPNAVALVDAFDFKDVTLGSVLGRYDGNVYENLF 633

  Fly   641 ESTKKNPLNKEPVNGAFHKYLKP 663
            |..||:||||..|:.:::|:|||
Mouse   634 EWAKKSPLNKTEVHESYYKHLKP 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5009	NP_611264.2	AXO	8..645	CDD:173839	281/651 (43%)
		PLN02443	10..669	CDD:178062	290/669 (43%)
Acox1	NP_001258827.1	AXO	3..638	CDD:173839	281/651 (43%)
		Microbody targeting signal	659..661

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	229	1.000	Domainoid score	I2465
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38299
Inparanoid	1	1.050	539	1.000	Inparanoid score	I1167
Isobase	1	0.950	-	0	Normalized mean entropy	S1686
OMA	1	1.010	-	-		QHG54939
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001030
OrthoInspector	1	1.000	-	-		otm42514
orthoMCL	1	0.900	-	-		OOG6_100457
Panther	1	1.100	-	-	LDO	PTHR10909
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2020
SonicParanoid	1	1.000	-	-		X618
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.810