Protein Alignment HLH54F and TCF21

DIOPT Version :9

• Sequence 1: NP_477302.1
• Gene: HLH54F / 37027
• FlyBaseID: FBgn0022740
• Length: 242
• Species: Drosophila melanogaster
• Sequence 2: NP_003197.2
• Gene: TCF21 / 6943
• HGNCID: 11632
• Length: 179
• Species: Homo sapiens
• Alignment Length: 108
• Identity: 56/108 - (51%)
• Similarity: 65/108 - (60%)
• Gaps: 17/108 - (15%)

  Fly     2 PRK------KRSSSPTEFFDDDFDEDASSQSSQ--PPVQRNAANARERMRMRVLSSAYGRLKTKL 58
            |:|      ||..:||:       :...|..||  ..|||||||||||.||||||.|:.||||.|
Human    49 PQKGRGGLGKRRKAPTK-------KSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTL 106

  Fly    59 PNIPPDTKLSKLDTLRLATLYIKQL--ITAVETGSHSQNHPHN 99
            |.:|||||||||||||||:.||..|  |.|.:...:...||.|
Human   107 PWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYENGYIHPVN 149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH54F	NP_477302.1	HLH	32..83	CDD:278439	40/50 (80%)
TCF21	NP_003197.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..87		16/44 (36%)
		bHLH_TS_TCF21_capsulin	77..140	CDD:381547	44/62 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149616
Domainoid	1	1.000	81	1.000	Domainoid score	I8521
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004410
OrthoInspector	1	1.000	-	-		otm40971
orthoMCL	1	0.900	-	-		OOG6_107588
Panther	1	1.100	-	-	O	PTHR23349
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5029
SonicParanoid	1	1.000	-	-		X3129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.770