DRSC/TRiP Functional Genomics Resources

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Protein Alignment HLH54F and BHLHE22

DIOPT Version :10

Sequence 1:NP_477302.1 Gene:HLH54F / 37027 FlyBaseID:FBgn0022740 Length:242 Species:Drosophila melanogaster
Sequence 2:NP_689627.1 Gene:BHLHE22 / 27319 HGNCID:11963 Length:381 Species:Homo sapiens


Alignment Length:73 Identity:29/73 - (39%)
Similarity:39/73 - (53%) Gaps:6/73 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 ASSQSSQPPVQRNA----ANARERMRMRVLSSAYGRLKTKLP--NIPPDTKLSKLDTLRLATLYI 80
            :||.||:...::.|    .|||||.||..|:.|...|:..:|  :.|...||||:.||.||..||
Human   229 SSSSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYI 293

  Fly    81 KQLITAVE 88
            .....|:|
Human   294 LMQAQALE 301

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HLH54FNP_477302.1 bHLH_TS_musculin_like 32..87 CDD:381429 23/60 (38%)
BHLHE22NP_689627.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 30..94
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 135..154
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 188..242 4/12 (33%)
bHLH_TS_bHLHe22_bHLHb5 243..312 CDD:381524 24/59 (41%)
Blue background indicates that the domain is not in the aligned region.

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