Protein Alignment HLH54F and TWIST2

DIOPT Version :9

• Sequence 1: NP_477302.1
• Gene: HLH54F / 37027
• FlyBaseID: FBgn0022740
• Length: 242
• Species: Drosophila melanogaster
• Sequence 2: NP_001258822.1
• Gene: TWIST2 / 117581
• HGNCID: 20670
• Length: 160
• Species: Homo sapiens
• Alignment Length: 101
• Identity: 35/101 - (34%)
• Similarity: 49/101 - (48%)
• Gaps: 22/101 - (21%)

  Fly     3 RKKRSSSPTEFFDDDFDEDAS----------SQSSQP----PVQRNAANARERMRMRVLSSAYGR 53
            ||:|.|..:       .||.|          |.|:|.    ..||..||.|||.|.:.|:.|:..
Human    31 RKRRYSKKS-------SEDGSPTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAA 88

  Fly    54 LKTKLPNIPPDTKLSKLDTLRLATLYIKQLITAVET 89
            |:..:|.:|.| ||||:.||:||..||..|...:::
Human    89 LRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQS 123

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH54F	NP_477302.1	HLH	32..83	CDD:278439	24/50 (48%)
TWIST2	NP_001258822.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63		10/38 (26%)
		bHLH_TS_TWIST2	51..132	CDD:381543	28/74 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149606
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840