DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HLH54F and Tcf24

DIOPT Version :9

Sequence 1:NP_477302.1 Gene:HLH54F / 37027 FlyBaseID:FBgn0022740 Length:242 Species:Drosophila melanogaster
Sequence 2:NP_001272354.1 Gene:Tcf24 / 100039596 MGIID:3780500 Length:166 Species:Mus musculus


Alignment Length:125 Identity:40/125 - (32%)
Similarity:56/125 - (44%) Gaps:39/125 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MPRKKRSSSPTEFFDDDFDEDASSQSSQPPVQRN---------------------------AAN- 37
            |.|.:.:|||           .|::|:.||....                           ||| 
Mouse     1 MERGRPASSP-----------RSAESAAPPAAARDWSPGPTGTGPTGLSGVAARSGGGRPAAANA 54

  Fly    38 ARERMRMRVLSSAYGRLKTKLPNIPPDTKLSKLDTLRLATLYIKQLITAVETGSHSQNHP 97
            ||||.|::.|..|:..|:..||::||||||||||.|.|||.||..|..:::..:.:...|
Mouse    55 ARERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDDTDAPGDP 114

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HLH54FNP_477302.1 HLH 32..83 CDD:278439 29/78 (37%)
Tcf24NP_001272354.1 bHLH_TS_TCF24 49..104 CDD:381553 30/54 (56%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167839679
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4029
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.830

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