DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5002 and AST56

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_565165.2	Gene:	AST56 / 844134	AraportID:	AT1G77990	Length:	677	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	150/548 - (27%)
Similarity:	263/548 - (47%)	Gaps:	77/548 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 STVTNKFPILKWLPRYRLEYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMGCFTYI 95
            |.:.:.||||.|..:|:|....:|.:||.|:....|||:|.|..:|||:|:||||::.:....|.
plant    87 SCLKSAFPILSWGRQYKLNLFKKDLMAGLTLASLCIPQSIGYANLAGLDPEYGLYTSVVPPLIYS 151

  Fly    96 VFGSCKDVTIATTAIMALMVNQYATISPD----------YAVLVCFLAGCIVLLLGLLNMGVLVR 150
            ..|:.:::.|...|:::|:::.......|          ....|.|.||....:.||..:|.||.
plant   152 TMGTSRELAIGPVAVVSLLLSSMVRDLQDPVTDPIAYRKIVFTVTFFAGAFQAIFGLFRLGFLVD 216

  Fly   151 FISIPVITGFTMAAATTIGSAQINNIVGLTSPSN--DLLPAWKNFFTHLTSIRLWDAL---LGVS 210
            |:|...:.||...||..||..|:..:.|||..:|  |::....:.|..|.  ..|..|   :|.|
plant   217 FLSHAALVGFMAGAAIVIGLQQLKGLFGLTHFTNKTDVVSVLSSVFHSLH--HPWQPLNFVIGSS 279

  Fly   211 SLVFLLLMTRVKDIKWGNRIFWKYLGLSRNALAVIFGTFLAYILSRDGNQPFRVTGNITAGVP-- 273
            .|:|:||...:.  |..|::||  :......::|:..|.:.| ||...::..::..:|..|..
plant   280 FLIFILLARFIG--KRNNKLFW--IPAMAPLISVVLATLIVY-LSNAESRGVKIVKHIKPGFNQL 339

  Fly   274 -----PFRLPPFSTTVDGEYVSFGEMISTVGASLGSIPLISILEIVAISKAFS--KGKIVDASQE 331
                 .|:.|..     |:....| :||.:         |::.|.:|:.::|:  ||..:|.::|
plant   340 SVNQLQFKSPHL-----GQIAKIG-LISAI---------IALTEAIAVGRSFATIKGYRLDGNKE 389

  Fly   332 MVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMALAFLTQTFYFIPKCT 396
            |:|:|..||.||.......||||:|||||.::|.:|.:...|....|:::|..||:..||.|...
plant   390 MMAMGFMNIAGSLSSCYVATGSFSRTAVNFSAGCETVVSNIVMAITVMISLEVLTRFLYFTPTAI 454

  Fly   397 LAAIIIAAMISLVELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGIGANMVYILYSSAR 461
            ||:||::|:..|:::.....:||..|.|....:......:|.|:|.|:|..:|.:...|:.||.|
plant   455 LASIILSALPGLIDVSGALHIWKLDKLDFLVLIAAFFGVLFASVEIGLLLAVGISFARIMLSSIR 519

  Fly   462 PHVDI--KLEK--INGHEVSVVDVKQ------------------KLDYASAEYLKEKV---VRFL 501
            |.::.  :|.|  |.|      |:.|                  .|.:|:|.::::::   |:.:
plant   520 PSIEALGRLSKTDIFG------DINQYPMANKTAGLLTLRISSPLLCFANANFIRDRILNSVQEI 578

  Fly   502 NNQNGETQLVVIKGEEINSIDYTVAMNI 529
            ..:..|.:::...|.::..:|.:..|.:
plant   579 EGEENEQEVLKENGLQVVILDMSCVMGV 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	149/543 (27%)
		HCO3_cotransp	103..>385	CDD:304903	83/305 (27%)
		STAS	469..>544	CDD:294402	13/84 (15%)
AST56	NP_565165.2	sulP	94..662	CDD:273284	148/541 (27%)
AST56	NP_565165.2	STAS	540..662	CDD:279997	8/67 (12%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		mtm1058
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.880