Protein Alignment CG5002 and SLC26A6

DIOPT Version :9

• Sequence 1: NP_611262.1
• Gene: CG5002 / 37025
• FlyBaseID: FBgn0034275
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_075062.2
• Gene: SLC26A6 / 65010
• HGNCID: 14472
• Length: 759
• Species: Homo sapiens
• Alignment Length: 631
• Identity: 150/631 - (23%)
• Similarity: 294/631 - (46%)
• Gaps: 125/631 - (19%)

  Fly    38 PILKWLPRYRL-EYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMGCFTYIVFGSCK 101
            |:|.|||||.: ::::.|.::|.:|.:..:||.:||.::|||.|.:||||:|...|.|.:||:.:
Human    76 PVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSR 140

  Fly   102 DVTIATTAIMALMVNQYA-TISP------------------DYAVLVCFLAGCIVLLLGLLNMGV 147
            .:::.|.|:|::||.... :::|                  ..|..:..|.|...:.|||::.|.
Human   141 HISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGF 205

  Fly   148 LVRFISIPVITGFTMAAATTIGSAQINNIVGLTSPSND---------LLPAWK----NFFTHLTS 199
            :|.::|.|::.|:|.|||..:..:|:..:.||...|:.         |...||    ...|.:|:
Human   206 VVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTA 270

  Fly   200 IRLWDALLGVSSLVFLLLMTRVKDIKWGNRIFWKYLGLSRNALAVIFGTFLAYILSRDGNQPFRV 264
                 |:.||..:|..||..:::.        ...:.:....|.:|..|.::|.:.........|
Human   271 -----AVAGVVLVVVKLLNDKLQQ--------QLPMPIPGELLTLIGATGISYGMGLKHRFEVDV 322

  Fly   265 TGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASLGSIPLISILEIVAISKAFS--KGKIVD 327
            .|||.||:    :||.:...        ::.|.:..|..:|.::.....:::.|.|:  .|..||
Human   323 VGNIPAGL----VPPVAPNT--------QLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVD 375

  Fly   328 ASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMALAFLTQTFYFI 392
            ::||:||||:.|::|......||:.|.:|:.|..::|..:.:.||::...:|:.:..|.:.|:.:
Human   376 SNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDL 440

  Fly   393 PKCTLAAIIIAAMISLV-ELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGIGANMVYIL 456
            ||..||||||..:..:: :|..::.:||:.:.||..::||....:..:|:.|::..:..:::.::
Human   441 PKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVV 505

  Fly   457 YSSARPHVDI-----------------KLEKINGHEVSVVDVKQKLDYASAEY----LKEKV--- 497
            ..:..||..:                 :.:::.|  |.|......:.:|:||:    ||::.
Human   506 VRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRG--VKVFRSSATVYFANAEFYSDALKQRCGVD 568

  Fly   498 VRFLNNQ-------NGETQLVVIKGEE------INSIDYTVAMNIVSMKGDLEALN---CAMICW 546
            |.||.:|       ..:.:|..::.||      .:....:|::|:.:...|:.:.|   |.|:
Human   569 VDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMM-- 631

  Fly   547 NWNIASAGVVCRLNNDLRPIFKFDLSLEEVVA-GHFDSPSNTASTV 591
              .::|..                 .:|:..| |..||.:...||:
Human   632 --QVSSGD-----------------KMEDATANGQEDSKAPDGSTL 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	143/601 (24%)
		HCO3_cotransp	103..>385	CDD:304903	73/315 (23%)
		STAS	469..>544	CDD:294402	20/97 (21%)
SLC26A6	NP_075062.2	sulP	76..738	CDD:273284	150/631 (24%)
		HCO3_cotransp	<299..451	CDD:304903	46/163 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	636..657		5/37 (14%)
		STAS_SulP_like_sulfate_transporter	<656..735	CDD:132913	2/3 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750