DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and slc26a6l

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_001107889.1	Gene:	slc26a6l / 559448	ZFINID:	ZDB-GENE-080220-10	Length:	808	Species:	Danio rerio

Alignment Length:	545	Identity:	131/545 - (24%)
Similarity:	255/545 - (46%)	Gaps:	122/545 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 TVTNKFPILKWLPRYRL-EYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMGCFTYI 95
            ::....|:|.|||||.: :|.|.|.|:|.:||:..:||.:||.::|.|.|.:|||::......|.
Zfish    54 SIVGFLPVLSWLPRYSIWDYGMPDLISGISVGIMHLPQGMAYALLASLPPVFGLYTSLYPSLIYF 118

  Fly    96 VFGSCKDVTIATTAIMALMVNQYA-TISPD----------------------YAVLVC----FLA 133
            :||:.:.:::.|..|:::|:.... .::||                      |.|.|.    .|.
Zfish   119 IFGTSRHISVGTFTILSIMIGSVTERLAPDTDFLIYNGTNVTGEVDIASRDLYRVQVAAAATVLG 183

  Fly   134 GCIVLLLGLLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLTSPSN-------------- 184
            |.|.::|||:..|.:..::|.|::.|:|.||:.....||:..|:|: ||..
Zfish   184 GLIQVVLGLVQFGFVGTYLSEPLVRGYTTAASAHAVVAQLKYILGV-SPKRFNGPLSIVYTLVDL 247

  Fly   185 -DLLPAWKNFFTHLTSIRLWDALLGVSSLVFLLLMTRVKDIKWGNRIFWKYLGLSRNAL------ 242
             .|||.     |||.::        |:|:|.::::...|::              .|||
Zfish   248 FTLLPE-----THLPTL--------VASVVSIVVLITAKEL--------------NNALKKKMII 285

  Fly   243 -------AVIFGTFLAYILSRDGNQPFRVTGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGA 300
                   .::..|.:::....:.:....|.|:|.:|:.|..:|  :..:..|.|.....::.||.
Zfish   286 PIPVELCTIVVATVISFYTRLNESYKISVVGDIPSGLQPPSVP--NVYIFSEVVLDAFAMAIVGY 348

  Fly   301 SLGSIPLISILEIVAISKAFS--KGKIVDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNAS 363
            ::.          :::.|.|:  .|..|:::||:||||:.|.:|.|.....|..|.:|:.:..::
Zfish   349 AIS----------ISLGKTFALKHGYKVESNQELVALGLSNTVGGFFQCFSVCSSMSRSLIQEST 403

  Fly   364 GVKTPLGGAVTGALVLMALAFLTQTFYFIPKCTLAAIIIAAMISLV-ELHKIKDMWKSKKKDLFP 427
            |.||.:.|.|:|.:||:.:..|...|..:||..|:||:...:..:. :.:.|..:|:|.|.||..
Zfish   404 GGKTQIAGVVSGVIVLVTVLKLGSLFQELPKAVLSAIVFVNLKGMFKQYYDIVTLWRSNKIDLLI 468

  Fly   428 FVVTVLTCMFWSLEYGILCGIGANMVYILYSSARP-------------HVDIKLEK----INGHE 475
            ::||.::.:.::|:.|:...:|..::.:::.:.||             ::|::..|    :.|
Zfish   469 WLVTFVSTVLFNLDMGLGASMGFALLTVIFRTQRPSYALLGHLPGTELYLDMETHKEVREVPG-- 531

  Fly   476 VSVVDVKQKLDYASAEY----LKEK 496
            :::......:.:|:||.    ||:|
Zfish   532 ITIFRSSATMYFANAELYLEALKKK 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	131/541 (24%)
		HCO3_cotransp	103..>385	CDD:304903	75/338 (22%)
		STAS	469..>544	CDD:294402	8/36 (22%)
slc26a6l	NP_001107889.1	Sulfate_transp	77..472	CDD:279284	106/434 (24%)
		HCO3_cotransp	<338..449	CDD:304903	33/120 (28%)
		STAS_SulP_like_sulfate_transporter	<710..777	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.750