DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and CG9717

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster

Alignment Length:	591	Identity:	226/591 - (38%)
Similarity:	328/591 - (55%)	Gaps:	43/591 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EQLPNVSTLIRDGGRKLC--------RPSTVTNKFPILKWLPRYRLEYIMQDFIAGFTVGLTTIP 67
            ||.|:.|.|  :|.:..|        |..|:..:||||.|||:|:.:||..|.:||.:|.||.||
  Fly    41 EQGPDESCL--EGTQSCCSNLWSNIFRKKTLYKRFPILVWLPQYKKDYIFGDIVAGISVALTVIP 103

  Fly    68 QAIAYGVVAGLEPQYGLYSAFMGCFTYIVFGSCKDVTIATTAIMALMVNQYATISPDYAVLVCFL 132
            ||:||..:|||:.|||||:.|:|||.||..||.|||.|..|||.||:..|.|..|...|.|:.||
  Fly   104 QALAYAGIAGLDLQYGLYACFLGCFIYIFIGSSKDVPIGPTAISALLSFQIAGGSWQIATLLTFL 168

  Fly   133 AGCIVLLLGLLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLTSPSNDLLPAWKNFFTHL 197
            .|.|.:|:|:..:|.|:.|:|.||..|||.|.:..|.|:|:.:.:|:.:..|..|..|.:....:
  Fly   169 TGLIEILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDFLGIKTSGNTFLQVWISIVNDI 233

  Fly   198 TSIRLWDALLGVSSLVFLLLMTRVKDIKWGNR------------IFWKYLGLSRNALAVIFGTFL 250
            .:|...|.:||:..:..||.:..:.....|.:            |||. :|.:||||.|.....|
  Fly   234 HNISWPDFILGIVCITLLLSLRALASCTLGPKEGKTTAQKLLTGIFWT-IGTARNALLVCGTAGL 297

  Fly   251 AYILSRDGNQPF-RVTGNITAGVPPFRLPPF-------STTVDGEYV----SFGEMISTVGASLG 303
            .|.|..:|.:.. :..|.:..|:|.|:.|||       .||  ||.:    ||.:|:||:|:.|.
  Fly   298 GYWLFVNGKENLVKTVGFVPKGLPSFQPPPFHMDAVVNETT--GEVLQEAQSFWDMVSTLGSGLI 360

  Fly   304 SIPLISILEIVAISKAFSKGKIVDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTP 368
            .:|||::||.:|:.:||:.||..||:||::|.|:||:..|||..:...|...|.|:.|||||:|.
  Fly   361 VVPLIALLETMAVVQAFADGKPTDATQELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQ 425

  Fly   369 LGGAVTGALVLMALAFLTQTFYFIPKCTLAAIIIAAMISLVELHKIKDMWKSKKKDLFPFVVTVL 433
            |....|..:|::||.:||..||:|||..||:|||||:|.:|:...||.||.|||.||.|.:....
  Fly   426 LSNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAVIFMVQYRVIKPMWHSKKTDLIPGLGAFF 490

  Fly   434 TCMFWSLEYGILCGIGANMVYILYSSARPHVDIK-LEKINGHEVSVVDVKQKLDYASAEYLKEKV 497
            .|:...|:.|||.|||.|:|:|||.:|||.:.|: |....|.:..::...:.|.:.|.|:::
  Fly   491 ACLVLPLQLGILVGIGINVVFILYQAARPKLRIETLATTTGLKYLMLTPDRCLIFPSMEFVR--- 552

  Fly   498 VRFLNNQNGETQL-VVIKGEEINSIDYTVAMNIVSMKGDLEALNCAMICWNWNIASAGVVCRLNN 561
             :.:|.|..::.| |||....|...|:|.|..|.:|..|.:.....:..:|.....|.|...||.
  Fly   553 -KVINKQGQKSTLPVVIDCTHIYGADFTAAKVISTMVMDFKLREQPLFFYNLQPRVAQVFEGLNK 616

  Fly   562 DLRPIF 567
            ||..|:
  Fly   617 DLVVIY 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	215/553 (39%)
		HCO3_cotransp	103..>385	CDD:304903	108/305 (35%)
		STAS	469..>544	CDD:294402	17/75 (23%)
CG9717	NP_651812.1	sulP	74..607	CDD:273284	209/539 (39%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	19/81 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439024
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	11	10.800