DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and CG9702

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster

Alignment Length:	617	Identity:	225/617 - (36%)
Similarity:	336/617 - (54%)	Gaps:	63/617 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RKLCRPSTVTNKFPILKWLPRYRLEYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFM 89
            |.:.|..|:..:.|.|.|||.|..:..:.|.|||||||||.|||.:||..|.||.|:||||.:||
  Fly    66 RNIFRKKTLLKRLPFLTWLPHYNRQDCIGDLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFM 130

  Fly    90 GCFTYIVFGSCKDVTIATTAIMALMVNQYATISPDYAVLVCFLAGCIVLLLGLLNMGVLVRFISI 154
            |||.|::.|:|||.||.:||:.:||..|:|..|...:||:.||.|.|.:|:.:..:|.||.|:|.
  Fly   131 GCFVYVLLGTCKDSTIGSTAVASLMTFQFAQGSWQRSVLLTFLTGIIEILMAIFKLGCLVEFVSG 195

  Fly   155 PVITGFTMAAATTIGSAQINNIVGLTSPSNDLLPAWKNFFTHLTSIRLWDALLGVSSLVFLLLMT 219
            ||..|||.|.|..:.::|:.:::|:.|.....|..|.:.|..:.::|:.|..||...::.||.|.
  Fly   196 PVSAGFTSAVALIVSTSQMRSMLGVKSDGGSFLATWISMFRDIENVRVADTCLGFGCVILLLAMR 260

  Fly   220 RVKDIKWG--------------NRIFWKYLGLSRNALAVIFGTFLAYILSRDGNQPFRVTGNITA 270
            .:.....|              |.:. |:|..||||..||..|.:...|..:|..|||:||||..
  Fly   261 SLGKFTIGPKDESRRNGFQRVVNTVI-KFLSTSRNASVVILFTAVTMYLDANGTNPFRLTGNIPK 324

  Fly   271 GVPPFRLPPFS------------TTVDGEYVSFGEMISTVGASLGSIPLISILEIVAISKAFSKG 323
            |:|...|||||            ..|:|:  :|.||:.::|..|..:||:::||.:::.|||:||
  Fly   325 GMPTPSLPPFSIEPQPGNETAGIPAVEGQ--TFPEMVQSLGYGLVIVPLMALLETMSVCKAFAKG 387

  Fly   324 KIVDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMALAFLTQT 388
            |.:|.:|||:|.|:.||..|........|...|:|||||||.:|.:.....|.:|::||.|||:.
  Fly   388 KQIDITQEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEY 452

  Fly   389 FYFIPKCTLAAIIIAAMISLVELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGIGANMV 453
            ..||||..||||||:|:|..|:...:..||:||:.||.|.::..:||:...||.||:..||.|::
  Fly   453 IAFIPKAVLAAIIISAVIFQVQYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLL 517

  Fly   454 YILYSSARPHVDI-KLEKINGHEVSVVDVKQKLDYASAEYLKEKVVRFLNNQNGETQLVVIKGEE 517
            :|||.:|||.|.: :||...|.....:...:.|.:.|.|:::..|:: |.:::  |..|||....
  Fly   518 FILYYAARPKVTLEQLETQQGIRFVKITPDRCLIFPSVEFVRNMVLK-LGSKS--TLPVVIDCTY 579

  Fly   518 INSIDYTVAMNIVSMKGD--------------------LEALNCAMI-CWNWNIASAGVVCRLNN 561
            |.:.|:|.|..|.|:..|                    .|.||..:: |:|.:        .||.
  Fly   580 IYAADFTAAKVISSIVDDFRRRQQKIIFFNLKPSVVSVFEGLNTRLVLCYNTH--------ALNQ 636

  Fly   562 DLRPIFKFDLSLEEVVAGHFDSPSNTASTVTI 593
            :||| .:.|||.......|.:|.:.|:..|::
  Fly   637 ELRP-DEPDLSRSVDSLDHAESGNGTSECVSM 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	212/575 (37%)
		HCO3_cotransp	103..>385	CDD:304903	108/307 (35%)
		STAS	469..>544	CDD:294402	21/94 (22%)
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	206/547 (38%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	19/90 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439028
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm51364
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
	11	10.800