DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and CG7912

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_651761.2	Gene:	CG7912 / 43561	FlyBaseID:	FBgn0039736	Length:	602	Species:	Drosophila melanogaster

Alignment Length:	583	Identity:	333/583 - (57%)
Similarity:	435/583 - (74%)	Gaps:	6/583 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRADEDNLYREQLPNVSTLIRDGGRKLCRPSTVTNKFPILKWLPRYRLEYIMQDFIAGFTVGLTT 65
            ||.:||:||||:||||...:....|..|...:|....|:..|||:|:|.::..|.:||.|||||.
  Fly     1 MRDNEDDLYRERLPNVCGAVSSKARSCCSMRSVHRYLPVTDWLPKYQLNFLAMDVVAGLTVGLTA 65

  Fly    66 IPQAIAYGVVAGLEPQYGLYSAFMGCFTYIVFGSCKDVTIATTAIMALMVNQYATISPDYAVLVC 130
            :|||||||.||.|.|.|||||||||.|.||:.|:|||:|:..||||||||..|...:|.||||:|
  Fly    66 VPQAIAYGAVANLPPAYGLYSAFMGGFVYILLGTCKDITVGPTAIMALMVQPYVDGNPAYAVLIC 130

  Fly   131 FLAGCIVLLLGLLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLTSPSNDLLPAWKNFFT 195
            ||:|||:.|:||||:|||:||||:||.||||||||.||.:.|:|::.|::|.::..|.:|..||.
  Fly   131 FLSGCIITLMGLLNLGVLMRFISVPVTTGFTMAAALTIATGQVNSLFGISSSASGFLNSWIYFFG 195

  Fly   196 HLTSIRLWDALLGVSSLVFLLLMTRVKDIKWGNRIFWKYLGLSRNALAVIFGTFLAYILSRDGNQ 260
            |:|..|..||:||..:||.||||.::|::.:|.:..|||:.|:|||:||:.|..|.|:|..||..
  Fly   196 HITQTRRNDAILGCCTLVLLLLMRQLKNLTFGFKSVWKYISLARNAVAVLIGILLCYLLKNDGKL 260

  Fly   261 PFRVTGNITAGVPPFRLPPFST--TVDGEYVSFGEMISTVGASLGSIPLISILEIVAISKAFSKG 323
            ||.|:|:||.|:|||:||||.|  ...||.:|||.|:|.||.:|.||||:||||.:|::||||||
  Fly   261 PFLVSGSITPGLPPFKLPPFHTEDPETGETISFGGMVSNVGTALVSIPLLSILESIAVAKAFSKG 325

  Fly   324 KIVDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMALAFLTQT 388
            |||||||||:|||:.||:.||..|||:||||||||:|||||||||||||||||||||.|||||.|
  Fly   326 KIVDASQEMIALGVSNILSSFFSSMPITGSFTRTAINNASGVKTPLGGAVTGALVLMTLAFLTTT 390

  Fly   389 FYFIPKCTLAAIIIAAMISLVELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGIGANMV 453
            |.:|||.||||||||||..:||...|.::|::||:|:.||:||||||:||:||||::.||..|.:
  Fly   391 FAYIPKATLAAIIIAAMFFMVEYETIGEIWRAKKRDMLPFLVTVLTCVFWTLEYGMVVGIVFNAL 455

  Fly   454 YILYSSARPHVDIKLEKINGHEVSVVDVKQKLDYASAEYLKEKVVRFLNNQNGE----TQLVVIK 514
            ::||.|.:|...:..||.||.||::.|:|..:|||:|||||..:|..:..:|.|    |.|||||
  Fly   456 FLLYKSMKPQFFLTTEKFNGIEVTMADLKGSVDYAAAEYLKMSLVSHVTQRNSEGSAPTTLVVIK 520

  Fly   515 GEEINSIDYTVAMNIVSMKGDLEALNCAMICWNWNIASAGVVCRLNNDLRPIFKFDLSLEEVV 577
            |.||.|||.|||:|:.|::.||..|.|.||||||:|.:|||:||::..||.:|||..|..:::
  Fly   521 GHEIASIDTTVALNLKSLREDLALLKCDMICWNWSIPAAGVICRMDRKLRSMFKFSKSFPDLM 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	312/533 (59%)
		HCO3_cotransp	103..>385	CDD:304903	173/283 (61%)
		STAS	469..>544	CDD:294402	40/78 (51%)
CG7912	NP_651761.2	sulP	38..542	CDD:273284	296/503 (59%)
CG7912	NP_651761.2	STAS	485..582	CDD:294402	50/96 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439022
Domainoid	1	1.000	214	1.000	Domainoid score	I761
eggNOG	1	0.900	-	-		E1_COG0659
Homologene	1	1.000	-	-		H116749
Inparanoid	1	1.050	254	1.000	Inparanoid score	I1009
Isobase	1	0.950	-	0	Normalized mean entropy	S2728
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm25858
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	P	PTHR11814
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
	15	14.790