Protein Alignment CG5002 and SLC26A5

DIOPT Version :9

• Sequence 1: NP_611262.1
• Gene: CG5002 / 37025
• FlyBaseID: FBgn0034275
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_945350.1
• Gene: SLC26A5 / 375611
• HGNCID: 9359
• Length: 744
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 130/572 - (22%)
• Similarity: 259/572 - (45%)
• Gaps: 93/572 - (16%)

  Fly    28 CRPSTVTN----KFPILKWLPRYRL-EYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSA 87
            |.|..:.|    ..||.||||.|:. ||::.|.::|.:.|:..:||.:|:.::|.:.|.:||||:
Human    52 CTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSS 116

  Fly    88 FMGCFTYIVFGSCKDVTIATTAIMALMVNQYAT-ISPD-----------------------YAVL 128
            |.....|...|:.:.::|...|:::||:...|. :.||                       .|:.
Human   117 FYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMS 181

  Fly   129 VCFLAGCIVLLLGLLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGL-TSPSNDLLPAWKN 192
            |..|:|.|...||:...|.:..:::.|::.|||.|||..:.::.:..:.|: |...:.:.....:
Human   182 VTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYS 246

  Fly   193 FFTHLTSIR-LWDALLGVSSLVFLLLMTRVKDIKWGNRIFWKYL--GLSRNALAVIFGTFLAYIL 254
            ....|.::: |....|||..:||.||:..    |..|..|.:.|  .:.....||:.||.::...
Human   247 TVAVLQNVKNLNVCSLGVGLMVFGLLLGG----KEFNERFKEKLPAPIPLEFFAVVMGTGISAGF 307

  Fly   255 SRDGNQPFRVTGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASLGSIPLISILEIVAISKA 319
            :...:....|.|.:..|:    |||.:......::.:.:.|        :|.::.....::::|.
Human   308 NLKESYNVDVVGTLPLGL----LPPANPDTSLFHLVYVDAI--------AIAIVGFSVTISMAKT 360

  Fly   320 FSK--GKIVDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMAL 382
            .:.  |..||.:||::|||:||.:||...:..::.|.:|:.|...:|.||.|.|.:...::|:.:
Human   361 LANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVI 425

  Fly   383 AFLTQTFYFIPKCTLAAIIIAAMISL-VELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILC 446
            ......|..:|:..|:||:|..:..: ::...:...|::.|.:|..::.|.::.:|..|:||::.
Human   426 LATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLIT 490

  Fly   447 GIGANMVYILYSSARP-------------HVDI----KLEKINGHEVSVVDVKQKLDYASAEY-- 492
            .:...::.::|.:..|             ::||    ::::|.|  :.:..:...:.||:::.
Human   491 AVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPG--IKIFQINAPIYYANSDLYS 553

  Fly   493 --LKEKV------------------VRFLNNQNGETQLVVIKGEEINSIDYT 524
              ||.|.                  .:.:.|.|.....||....|::..|.|
Human   554 NALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDAT 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	127/560 (23%)
		HCO3_cotransp	103..>385	CDD:304903	71/311 (23%)
		STAS	469..>544	CDD:294402	14/78 (18%)
SLC26A5	NP_945350.1	sulP	66..709	CDD:273284	127/558 (23%)
		STAS_SulP_like_sulfate_transporter	526..694	CDD:132913	14/82 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	718..744

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1414
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750