DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5002 and Slc26a10

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_001128067.2	Gene:	Slc26a10 / 366909	RGDID:	1564851	Length:	684	Species:	Rattus norvegicus

Alignment Length:	459	Identity:	114/459 - (24%)
Similarity:	218/459 - (47%)	Gaps:	53/459 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KFPILKWLPRYRLE-YIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMGCFTYIVFGS 99
            :.|.|:|||:||.. :::.|.:||.|||:..:||.:|:.::..:.|.:|||::|.....|.:.|:
  Rat    89 RLPPLRWLPQYRWRAWLLGDAVAGITVGVVHVPQGMAFALLTSVPPVFGLYTSFFPVLIYSLLGT 153

  Fly   100 CKDVTIATTAIMALMVNQYA-TISPD--------------------YAVLVCFLAGCIVLLLGLL 143
            .:.::..|.|:::||..... .:.|:                    .|..|.|.:|.::|.:.:|
  Rat   154 GRHLSTGTFAVLSLMTGSVVERVVPEPLAGNLSGIEREKLEAQRIGAAAAVAFGSGALMLGMFVL 218

  Fly   144 NMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLTSPSN-DLLPAWKNFFTHLTSI-RLWDAL 206
            .:|||..|:|.||:...|..||..:..:|:.:::||:.|.. .....:|.....|::: :...|.
  Rat   219 QLGVLSTFLSEPVVKALTSGAALHVLVSQLPSLLGLSLPRQIGCFSLFKTLAAVLSALNQSSPAE 283

  Fly   207 LGVSSLVFLLLMTRVKD--IKWGNRIFWKYLGLSRNALAVIFGTFLAYILSRDGNQPFRVTGNIT 269
            |.:|:| .|.|:..||:  :::.:|:.....|   ..:.|:..|.|.:..|.|.....:|.|.:.
  Rat   284 LTISAL-SLALLVPVKELNVRFRDRLPTPIPG---EVVMVLLATVLCFTSSLDSRYNVQVVGLLP 344

  Fly   270 AGVPPFRLPPFSTTVD------GEYVSFGEMISTVGASLGSIPLISILEIVAISKAFSKGKIVDA 328
            .|.|...||    |:|      .:.:....:...|..||.||            .|......:|.
  Rat   345 GGFPQPLLP----TLDDLPRILADSLPISLVTFAVSTSLASI------------YADKYSYTIDP 393

  Fly   329 SQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMALAFLTQTFYFIP 393
            :||::|.|:.|::.|.....|.:.:...|::...:|..|.|.|..:..:||..|.:|...||::|
  Rat   394 NQELLAHGVSNLISSLFSCFPNSATLATTSLLVDAGGNTQLSGLFSCTVVLSVLLWLGPFFYYLP 458

  Fly   394 KCTLAAIIIAAMISL-VELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGIGANMVYILY 457
            |..||.|.|::|..: .::.::..:|...:.|...::||.:..:..:::.|:..|:..:||.::.
  Rat   459 KAVLACINISSMRQMFFQMQELPQLWHVSRVDFAVWMVTWVAVVTLNVDLGLAVGVVVSMVTVVC 523

  Fly   458 SSAR 461
            .:.|
  Rat   524 RTQR 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	114/459 (25%)
		HCO3_cotransp	103..>385	CDD:304903	72/312 (23%)
		STAS	469..>544	CDD:294402
Slc26a10	NP_001128067.2	sulP	91..664	CDD:273284	114/457 (25%)
Slc26a10	NP_001128067.2	STAS_SulP_like_sulfate_transporter	553..661	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820