DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and Slc26a9

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_796217.2	Gene:	Slc26a9 / 320718	MGIID:	2444594	Length:	790	Species:	Mus musculus

Alignment Length:	571	Identity:	128/571 - (22%)
Similarity:	244/571 - (42%)	Gaps:	93/571 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PILKWLPRYRL-EYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMGCFTYIVFGSCK 101
            |:|.|||:|:: :||:.|.:.|.:.|...:||.:|:.::|.|....||||:|....||...|...
Mouse    57 PVLSWLPKYKIKDYIIPDLLGGLSGGCIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGIH 121

  Fly   102 DVTIATTAIMALMV-NQYATISPD---------------------------YAVLVCFLAGCIVL 138
            .:...|.|:::::| |....::|:                           .|.|.| |...|.:
Mouse   122 QMVPGTFAVISILVGNICLQLAPESKFQIFNNVTNETYVDTAAMEAERLHVSATLAC-LTAVIQM 185

  Fly   139 LLGLLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLTSPS----NDLLPAWKNFFTHLTS 199
            .||.:..|.:..::|...|.||..||...|..:.:..|.|||.||    ..::..:.:...:|..
Mouse   186 ALGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPH 250

  Fly   200 IRLWDALLGVSSLVFLLLMTRVKDI--KWGNRIFWKYLGLSRNALAVIFGTFLAYILSRDGNQPF 262
            ..:...:..:.|.|||:|   ||::  ::.::|   :..:....:.|:..|.::...........
Mouse   251 TNIASLIFALVSGVFLVL---VKELNARYMHKI---HFPIPTEMIVVVVATAISGSCKMPKKYHM 309

  Fly   263 RVTGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASLGSIPLISILEIVAISK--AFSKGKI 325
            ::.|.|..|.|        |.|......:.:|:.|.    .|:.::..:..:|:.:  |...|..
Mouse   310 QIVGEIRQGFP--------TPVAPMVSQWKDMVGTA----FSLAIVGYVINLAMGRTLASKHGYD 362

  Fly   326 VDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMALAFLTQTFY 390
            ||::|||:|||..|..|||.....:..:.:.|...:.:|.|:.:.......:|::.:..|....|
Mouse   363 VDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGSYLY 427

  Fly   391 FIPKCTLAAII-IAAMISLVELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGIGANMVY 454
            .:||..|.|:| :....||.:|.....:|:..|.|...:||:.|:..|.||.||:..|:..:::.
Mouse   428 PLPKAVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCVWVVSFLSSFFLSLPYGVAVGVAFSILV 492

  Fly   455 ILYSS-----------------ARPHVDIKLEKINGHEVSVVDVKQKLDYASAEYLKEKVV---- 498
            :::.:                 ..|....:.::|.|  |.:|.....|.:|::|..::||:
Mouse   493 VIFQTQFRNGSTLAQVMDTDIYVNPKTYNRAQEIAG--VKIVTYCSPLYFANSEIFRQKVIAKTG 555

  Fly   499 -----------RFLNNQNGETQLVVIKGEEINSIDYTVAMNIVSMKGDLEA 538
                       ::|..|...|.:...:.:.:.....||::.  .::.|.|:
Mouse   556 MDPQKVLLAKQKYLRKQEKRTAIPTQQRKSLFMKTKTVSLQ--ELQQDFES 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	128/571 (22%)
		HCO3_cotransp	103..>385	CDD:304903	65/317 (21%)
		STAS	469..>544	CDD:294402	16/85 (19%)
Slc26a9	NP_796217.2	sulP	57..733	CDD:273284	128/571 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810