DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and Slc26a7

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	XP_038965346.1	Gene:	Slc26a7 / 297910	RGDID:	1310846	Length:	692	Species:	Rattus norvegicus

Alignment Length:	573	Identity:	134/573 - (23%)
Similarity:	255/573 - (44%)	Gaps:	95/573 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RDGGRKLCRPSTVTNKFPILKWLPRYRL-EYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGL 84
            |:..::.|:     .:.|||:|.|:|.| |.::.|.::|..:.:..:.|.:::.:::.:.|.:||
  Rat    21 REDIKQWCK-----RRLPILEWAPQYNLKENLLPDTVSGVLLAVQQVTQGLSFAILSSVHPVFGL 80

  Fly    85 YSAFMGCFTYIVFGSCKDVTIATTAIMALM-----------VNQYATISPDYAVL---------- 128
            |.:......|.:||..:.|...|.|:.:|:           .|:..|...:.:||
  Rat    81 YGSLFPAIIYAIFGMGRHVATGTFALTSLISANAVERLVPQSNRNLTTQSNSSVLGLSEFELQRI 145

  Fly   129 -----VCFLAGCIVLLLGLLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLTSP--SNDL 186
                 |.||.|.|.|::.:|.:|.....::.|||:..|..|||.:.::|:..::|:..|  |..|
  Rat   146 GVAAAVSFLGGVIQLVMFVLQLGNATFLLTEPVISAMTTGAATHVVTSQVKYLLGIKMPYISGPL 210

  Fly   187 --LPAWKNFFTHLTSIRLWDALLGVSSLVFLLLMTRVKDIKWGNRIFWKYLG--LSRNALAVIFG 247
              ...:...|.::.|::|...||.:.|:|.|:|   ||::   |..|.:.:.  |..:.:.:|..
  Rat   211 GFFYIYAYVFENIKSVQLEALLLSLLSIVVLVL---VKEL---NEQFKRKIKVVLPVDLVLIIAA 269

  Fly   248 TFLAYILSRDGNQPFRVTGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASLGSIPLISILE 312
            :|..|..:.:......|.|.|..|:||.|.||.:            ::|.|......:.|:..:.
  Rat   270 SFACYCTNMENTYGLEVVGRIPKGIPPPRAPPMN------------ILSAVLTEAFGVALVGYVA 322

  Fly   313 IVAISKAFSKGKI---VDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVT 374
            .:|:::..:| |.   ||.:||.:|.|:.|::.||:..:|...:..|||...::|.||.:...::
  Rat   323 SLALAQGSAK-KFKYSVDDNQEFLAHGLSNVIPSFLFCIPSAAAMGRTAGLYSTGAKTQVACLIS 386

  Fly   375 GALVLMALAFLTQTFYFIPKCTLAAIIIAAMIS-LVELHKIKDMWKSKKKDLFPFVVTVLTCMFW 438
            ...||:.:..:....|::|.|.||:||:..:.. |::...:|..|...|.|...::.|.:..:.:
  Rat   387 CIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWISTYIFTICF 451

  Fly   439 SLEYGILCGIGANMVYILYSSARPHVDIKLEKINGHEVSVVDVKQKLDYASAEYLKEKVVRFLNN 503
            :...|:|.|:...:..:|....|           ...:|:.|:|:.       .||.|...:.|.
  Rat   452 AANVGLLFGVVCTIAIVLGRFPR-----------AKTLSITDMKEM-------ELKVKTETYDNT 498

  Fly   504 QN----GETQLVVI-----KGEEINSIDYT-------VAMNIVSMKGDLEALN 540
            :|    ..|.:.|.     .|..:.|:..|       ..:.|:|:...|..||
  Rat   499 ENWPPSKSTNVKVFPGSLKTGSNVRSLSVTPRRMENSQQIKIISINNPLVFLN 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	132/558 (24%)
		HCO3_cotransp	103..>385	CDD:304903	78/316 (25%)
		STAS	469..>544	CDD:294402	18/88 (20%)
Slc26a7	XP_038965346.1	sulP	33..673	CDD:273284	132/556 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820