Protein Alignment CG5002 and SLC26A2

DIOPT Version :9

• Sequence 1: NP_611262.1
• Gene: CG5002 / 37025
• FlyBaseID: FBgn0034275
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_000103.2
• Gene: SLC26A2 / 1836
• HGNCID: 10994
• Length: 739
• Species: Homo sapiens
• Alignment Length: 623
• Identity: 144/623 - (23%)
• Similarity: 265/623 - (42%)
• Gaps: 126/623 - (20%)

  Fly    28 CRPSTVTNK----FPILKWLPRYRL-EYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSA 87
            |.|:...|.    .|:|:|||:|.| :.|:.|.::|..||:..:||:|||.::||.||.||||::
Human    80 CSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTS 144

  Fly    88 FMGCFTYIVFGSCKDVTIATTAIMALMVNQ------------YATISPD---------------- 124
            |.....|.:.|:.:.:::....::.||:.:            .|..:|.
Human   145 FFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSD 209

  Fly   125 -------YAVL----VCFLAGCIVLLLGLLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVG 178
                   ||::    |.|:||...:.:|...:|.:..::|..:::||...|:.||.::|...::|
Human   210 RICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLG 274

  Fly   179 LTSPSND----LLPAWKNFFTHLTSIRLWDALLGVSSLVFLLLMTRVKDIKWGNRIFWKYL--GL 237
            |..|..:    |:..|.:.|.::....|.|.   ::||:.||::...|::   |..|...|  .:
Human   275 LNLPRTNGVGSLITTWIHVFRNIHKTNLCDL---ITSLLCLLVLLPTKEL---NEHFKSKLKAPI 333

  Fly   238 SRNALAVIFGTFLAYILSRDGNQPFRVTGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASL 302
            ....:.|:..|..::......|....:.|:|..|..|.::|.::            :|.:|....
Human   334 PIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWN------------LIPSVAVDA 386

  Fly   303 GSIPLISILEIVAISKAFSK--GKIVDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGV 365
            .:|.:|.....|::|:.|:|  |..|.|:|||.|:|.|||:.||......:.:..:|.|..::|.
Human   387 IAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGC 451

  Fly   366 KTPLGGAVTGALVLMALAFLTQTFYFIPKCTLAAIIIAAMISLVELHKIKD---MWKSKKKDLFP 427
            .|.|.|.||..::|:.|..:...||.:.|..|..|.|..:..  .|.|.:|   ||...:.|...
Human   452 HTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRG--ALRKFRDLPKMWSISRMDTVI 514

  Fly   428 FVVTVLTCMFWSLEYGILCGIGANMVYILYSSARPHVDI--------KLEKINGHE--------- 475
            :.||:|:....|.|.|:|.|:..::..::..:.:|...:        ..|.::.::
Human   515 WFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIK 579

  Fly   476 ------------------------VSVVDVKQKLDYASAEYLKEKVVRF----------LNNQNG 506
                                    |:.:.:|.....|:...:|||||..          |::...
Human   580 IFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQLSHDPL 644

  Fly   507 ETQLVVIKGEEINSIDYTVAMNIVSMKGDLEALNCAMI 544
            |...:||....|..:|......:..::.|.||:...::
Human   645 ELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVL 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	141/615 (23%)
		HCO3_cotransp	103..>385	CDD:304903	74/328 (23%)
		STAS	469..>544	CDD:294402	18/117 (15%)
SLC26A2	NP_000103.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		sulP	94..715	CDD:273284	141/609 (23%)
		STAS	570..707	CDD:132911	17/113 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820