DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and Slc26a6

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	XP_036010526.1	Gene:	Slc26a6 / 171429	MGIID:	2159728	Length:	758	Species:	Mus musculus

Alignment Length:	575	Identity:	151/575 - (26%)
Similarity:	280/575 - (48%)	Gaps:	87/575 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 STVTNKFPILKWLPRYRL-EYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMGCFTY 94
            |.:....|:|.|||||.: |:::.|.::|.:|.:..:||.:||.::|||.|.:||||:|...|.|
Mouse    71 SLLLQHVPVLGWLPRYPVREWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPMFGLYSSFYPVFIY 135

  Fly    95 IVFGSCKDVTIATTAIMALMVNQYA-TISPDYAVL-----------------VCFLAGCIVLLLG 141
            .:||:.:.:::.|.|:|::||.... :::.|.|.:                 :.||.|...:.||
Mouse   136 FLFGTSRHISVGTFAVMSVMVGSVTESLTADKAFVQGLNATADDARVQVAYTLSFLVGLFQVGLG 200

  Fly   142 LLNMGVLVRFISIPVITGFTMAAATTIGSAQINNIVG--LTSPSNDLLPAWKNFFTHL-TSIRLW 203
            |::.|.:|.::|.|::..:|.||:..:..:|:..:.|  |:|.|..|    ...:|.| ...:|.
Mouse   201 LVHFGFVVTYLSEPLVRSYTTAASVQVLVSQLKYVFGIKLSSHSGPL----SVIYTVLEVCAQLP 261

  Fly   204 DALLG--VSSLV--FLLLMTRVKDIKWGNRIFWKYLGLSRNALAVIFGTFLAYILSRDGNQPFRV 264
            :.:.|  |:::|  ..|::.::.:.|...|:   .|.:....|.:|..|.::|.:..:......|
Mouse   262 ETVPGTVVTAIVAGVALVLVKLLNEKLHRRL---PLPIPGELLTLIGATGISYGVKLNDRFKVDV 323

  Fly   265 TGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASLGSIPLISILEIVAISKAFS--KGKIVD 327
            .||||.|:    :||.:...        |:.:|:..:..:|.::.....:::.|.|:  .|..||
Mouse   324 VGNITTGL----IPPVAPKT--------ELFATLVGNAFAIAVVGFAIAISLGKIFALRHGYRVD 376

  Fly   328 ASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMALAFLTQTFYFI 392
            ::||:||||:.|::|.|....||:.|.:|:.|..::|..|.:.|||:...:|:.:..|.:.|..:
Mouse   377 SNQELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQVAGAVSSLFILLIIVKLGELFRDL 441

  Fly   393 PKCTLAAIIIAAMISLV-ELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGIGANMVYIL 456
            ||..|||:||..:..:: :...|..:||:.:.||..::||.:..:..:|:.|:...|..:::.::
Mouse   442 PKAVLAAVIIVNLKGMMKQFSDICSLWKANRVDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVV 506

  Fly   457 YSSARPHVDI------------KLEKINGHEVSVVDV---KQKLDYASAEY----LKEK----VV 498
            .....||..:            ..|.....||..|.|   ...|.:|:||.    ||||    |.
Mouse   507 VRMQLPHYSVLGQVPDTDIYRDVAEYSGAKEVPGVKVFRSSATLYFANAELYSDSLKEKCGVDVD 571

  Fly   499 RFLNN-----QNGETQLVVIK----------GEEINSIDYTVAMNIVSMK-GDLE 537
            |.:..     :..|.:|..:|          ..:|:|:...|..|:..:| .|:|
Mouse   572 RLITQKKKRIKKQEMKLKRMKKAKKSQKQDASSKISSVSVNVNTNLEDVKSNDVE 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	150/570 (26%)
		HCO3_cotransp	103..>385	CDD:304903	76/308 (25%)
		STAS	469..>544	CDD:294402	25/96 (26%)
Slc26a6	XP_036010526.1	sulP	78..737	CDD:273284	150/568 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820