DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and slc26a3.3

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	XP_031754872.1	Gene:	slc26a3.3 / 101731072	XenbaseID:	XB-GENE-22062173	Length:	775	Species:	Xenopus tropicalis

Alignment Length:	589	Identity:	141/589 - (23%)
Similarity:	269/589 - (45%)	Gaps:	99/589 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 FPILKWLPRYRL-EYIMQDFIAGFTVGLTTIPQAIAYGVVAGLEPQYGLYSAFMGCFTYIVFGSC 100
            |||..|||.||. |:|:.|.::|.:.||..:.|.:|:.::..:.|.||||:||....||..||:.
Frog    58 FPIASWLPMYRFKEWILSDIVSGISTGLVAVLQGLAFALLVNVTPGYGLYAAFFPVITYFFFGTS 122

  Fly   101 KDVTIATTAIMALMV-NQYATISPD---------------------YAVLVCFLAGCIVLLLGLL 143
            :.:::....:::||| .....::||                     .|..|..|||...|.:|||
Frog   123 RHISVGPFPVLSLMVGTAVLRLAPDDPSISANNTEALTMLNEKRVVVAASVTVLAGIFQLAMGLL 187

  Fly   144 NMGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLT----SPSNDLLPAWKNFFTHLTSIRLWD 204
            .:|.:|.::|..:|:|||.|||..:..:|:..:.||.    |....|....|..|..:|...:.|
Frog   188 QIGFIVIYLSDSLISGFTTAAAIHVLVSQLKFVFGLKVEPFSGPLSLFYTLKGIFIQITDTNIAD 252

  Fly   205 ALLGVSSLVFLLLMTRVKDIKWGNRIFWKY-LGLSRNALAVIFGTFLAYILSRDGNQPFRVTGNI 268
            .   |:|::.::::..||:|  .:|...|. :.:....:..:..|.::|.|:........:.|.:
Frog   253 L---VTSIIIMVVVFVVKEI--NDRFKAKIPVPIPIEVIMTVIATGVSYALNFKDRYKVDIVGTL 312

  Fly   269 TAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASLGSIPLISILEIVAISKAFSKGKIVDASQEMV 333
            ..|..|...|  |.:|..:.|..|..|:.||.::.    .|:.::.::...:    :::.:||:|
Frog   313 EKGFQPPIAP--SLSVFQDCVGDGFSIAIVGFAVA----FSVAKVYSVKHDY----VINGNQELV 367

  Fly   334 ALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGG---AVTGALVLMALAFLTQTFYFIPKC 395
            |.|:.||.|........:.:.:|:||..::|.||.:.|   |:...:|::|:.||.:.   :.|.
Frog   368 AFGLSNIFGGCFKGFAASTALSRSAVQESTGGKTQIAGILSAIIVMIVILAIGFLIEP---LQKS 429

  Fly   396 TLAAIIIAAMIS-LVELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGIGANMVYILYSS 459
            .|.|::|..:.. |::.:::..:::..|.|:..::||.|..:...|:.|:..|:|..::.:::.:
Frog   430 VLGALVIINLKGMLMQFNELPVLFRKDKYDMLVWIVTFLGAVLLGLDLGLAAGVGFELLTVVFRA 494

  Fly   460 ARPHVDIKLEKINGHEVSVVDVKQKLDY--------------------ASAEYLKEKVV------ 498
            ..|... ::..:.|..:    .|.:.||                    |:.|:.|:||:
Frog   495 QFPKCS-QIANVGGSNI----YKNRKDYKNIYEPQGVKIFRCPSPVFFANIEFFKDKVIAAVGFN 554

  Fly   499 --RFLNNQN---GETQLVVIKGE-------EINSIDYTVAMNIVSMKGDLEALNCAM------IC 545
              |.|..:|   .:.:.::.|||       .||:.:|.:..:.......:|.|:...      |.
Frog   555 PLRILRKRNKALRKIRKLLSKGELQWTPKGMINTSNYNIDSDEELDNNHIEELDQPTYTADLPIT 619

  Fly   546 WNWN 549
            .|||
Frog   620 INWN 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	141/589 (24%)
		HCO3_cotransp	103..>385	CDD:304903	73/311 (23%)
		STAS	469..>544	CDD:294402	20/118 (17%)
slc26a3.3	XP_031754872.1	Sulfate_transp	73..466	CDD:395733	100/410 (24%)
slc26a3.3	XP_031754872.1	STAS_SulP_like_sulfate_transporter	517..693	CDD:132913	21/107 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D252952at33208
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920