DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5002 and slc26a11

DIOPT Version :9

Sequence 1:	NP_611262.1	Gene:	CG5002 / 37025	FlyBaseID:	FBgn0034275	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	XP_002937354.2	Gene:	slc26a11 / 100486579	XenbaseID:	XB-GENE-955145	Length:	594	Species:	Xenopus tropicalis

Alignment Length:	593	Identity:	230/593 - (38%)
Similarity:	333/593 - (56%)	Gaps:	67/593 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GRKL---------CRPSTVTNKFPILKWLPRYRLEYIMQDFIAGFTVGLTTIPQAIAYGVVAGLE 79
            ||:|         |  :::..:.|.|:|||||.|:::..|.|||.|||||.:|||:||..||||.
Frog    10 GRRLHPTLTCCFSC--NSLQKRLPFLQWLPRYSLQWLQLDIIAGITVGLTVVPQALAYAEVAGLP 72

  Fly    80 PQYGLYSAFMGCFTYIVFGSCKDVTIATTAIMALMVNQYATISPDYAVLVCFLAGCIVLLLGLLN 144
            .|:||||:|:|||.|...|:.||||:..||||:|:|..|.......|:|:.|::|||.|.:||||
Frog    73 VQFGLYSSFVGCFIYCFLGTSKDVTLGPTAIMSLLVFVYTLGDLSLAILLTFISGCIQLAMGLLN 137

  Fly   145 MGVLVRFISIPVITGFTMAAATTIGSAQINNIVGLTS-PSNDLLPAWKNFFTHLTSIRLWDALLG 208
            .|.|:.|||.|||..||.|||.||..:|:.|::||.. |...:|..::. |..|.|.|..||:||
Frog   138 FGFLLDFISYPVIKAFTSAAAITIAFSQVKNLLGLQDIPRQFILQVYQT-FRKLPSTRPGDAILG 201

  Fly   209 VSSLVFLLLMTRVKD------------------IKWGNRIFWKYLGLSRNALAVIFGTFLAYILS 255
            :..:..||.:..:||                  |.|       .:..:||||.|:....:||...
Frog   202 ILCIAILLALKWMKDHTSRPYQGMSICHRICYLIVW-------IMTTARNALIVVGAGLVAYSFH 259

  Fly   256 RDGNQPFRVTGNITAGVPPFRLPPFSTTVDGEYVSFGEMISTVGASLGSIPLISILEIVAISKAF 320
            ..|..||.:||....|:|.|:|||||........:|.||:..:|:.:..|||:.:||.|||::||
Frog   260 VMGLHPFILTGKTAKGLPQFQLPPFSEITPNGTKTFSEMVQVIGSGILIIPLMGLLESVAIARAF 324

  Fly   321 S--KGKIVDASQEMVALGMCNIMGSFVLSMPVTGSFTRTAVNNASGVKTPLGGAVTGALVLMALA 383
            :  ....:..:||::|:|:.||:|||:.|.||||||.|||:|:.:||.||.||.:||.|||::|.
Frog   325 ASQNNYRIKTNQELLAIGLTNILGSFLSSYPVTGSFGRTALNSQTGVCTPAGGIITGLLVLLSLG 389

  Fly   384 FLTQTFYFIPKCTLAAIIIAAMISLVELHKIKDMWKSKKKDLFPFVVTVLTCMFWSLEYGILCGI 448
            :||..||||||..|||:||.|:..:.:|...|.|||.|:.||.||.||.| ..||.::||||.|.
Frog   390 YLTPAFYFIPKAALAAVIICAVAPMFDLRICKSMWKVKRLDLIPFFVTFL-LSFWEIQYGILAGT 453

  Fly   449 GANMVYILYSSARPHVDIKLEKINGHEVSVVDVKQKLDYASAEYLKEKVVRFLNNQNGETQLVVI 513
            ..:::::.|..|||  :||:..::|   .::.....|.:.:.||||:|:.......: ..|.|.:
Frog   454 FVSIIFLCYPIARP--EIKVSDMDG---LILTPMSGLSFPAMEYLKDKIYEKTFTVS-SPQSVTL 512

  Fly   514 KGEEINSIDYTVAMNIVSMKGDLEALNCAMICWNWNIASAGVVCRLNNDLRP--IFKFDLS-LEE 575
            ....:.:|||||.:.:..:..:.:|..               ||...:.|:|  :..|..| |.|
Frog   513 DFTHVTAIDYTVVVGLAELLSEFKAQG---------------VCLTFSGLQPPLLHMFSSSGLTE 562

  Fly   576 VVAGHFDS 583
            :  .||.|
Frog   563 L--HHFHS 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5002	NP_611262.1	SUL1	36..564	CDD:223732	217/548 (40%)
		HCO3_cotransp	103..>385	CDD:304903	121/302 (40%)
		STAS	469..>544	CDD:294402	15/74 (20%)
slc26a11	XP_002937354.2	sulP	31..563	CDD:273284	222/561 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11814
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110