DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10931 and DCAF11

DIOPT Version :9

Sequence 1:NP_611261.1 Gene:CG10931 / 37024 FlyBaseID:FBgn0034274 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_001156956.1 Gene:DCAF11 / 80344 HGNCID:20258 Length:546 Species:Homo sapiens


Alignment Length:303 Identity:65/303 - (21%)
Similarity:117/303 - (38%) Gaps:79/303 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 VTGLKFSSNGENLVSSSGDRLLKLWDLSATRCIQSLAGHGDGVNDVAWS--AAGLIASCSDDMTV 121
            |..:..||:|..::..:.|..|.::|....|....:..|.|.||.||::  ::.::.|..||...
Human   268 VFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISSQILFSGGDDAIC 332

  Fly   122 RLWDARSKLCVKVLEGHSRYSFSCCFNPQANLLASTSFDETVRLWDVRTGKTLKIVHAHQDPITS 186
            ::||.|                                  |:|..|   .|.:..:..|||.||.
Human   333 KVWDRR----------------------------------TMREDD---PKPVGALAGHQDGITF 360

  Fly   187 VDFHRDGNIFVTSSYDGLVRLWDSSTGHVLKTLVDVDNIPVGYVKFSPNGRYILSSTLNNTLRLW 251
            :|...|....:::|.|..::|||..                   :|| :...:.:|....|.:.|
Human   361 IDSKGDARYLISNSKDQTIKLWDIR-------------------RFS-SREGMEASRQAATQQNW 405

  Fly   252 NYK---KPK------------CMRTYRGH--LNEFY-CSNSNFSTTGGIWIVSGSEDNTLCIWNL 298
            :|:   .||            .:.|||||  |:... |..|...:||..:|.||.....:.:::|
Human   406 DYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPIHSTGQQFIYSGCSTGKVVVYDL 470

  Fly   299 QTRELVQKISTEGDQILSTHCHPTANVIASGALQNSYAIKIWK 341
            .:..:|:|::.....:.....||....|.|.:...:  :::|:
Human   471 LSGHIVKKLTNHKACVRDVSWHPFEEKIVSSSWDGN--LRLWQ 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10931NP_611261.1 WD40 <48..341 CDD:225201 64/301 (21%)
WD40 49..341 CDD:238121 64/301 (21%)
WD40 repeat 59..96 CDD:293791 8/36 (22%)
WD40 repeat 102..137 CDD:293791 9/36 (25%)
WD40 repeat 142..178 CDD:293791 4/35 (11%)
WD40 repeat 185..220 CDD:293791 8/34 (24%)
WD40 repeat 227..263 CDD:293791 9/50 (18%)
WD40 repeat 271..309 CDD:293791 10/37 (27%)
WD40 repeat 314..340 CDD:293791 4/25 (16%)
DCAF11NP_001156956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..40
WD40 169..511 CDD:330360 64/301 (21%)
WD 1 170..210
WD40 repeat 180..214 CDD:293791
WD 2 216..258
WD40 repeat 221..263 CDD:293791
WD 3 263..302 8/33 (24%)
WD40 repeat 269..305 CDD:293791 7/35 (20%)
WD 4 305..345 15/76 (20%)
WD40 repeat 310..352 CDD:293791 14/78 (18%)
WD 5 353..392 14/58 (24%)
WD40 repeat 359..394 CDD:293791 10/54 (19%)
WD 6 435..480 11/44 (25%)
WD40 repeat 440..470 CDD:293791 7/29 (24%)
WD 7 481..520 5/33 (15%)
WD40 repeat 486..510 CDD:293791 4/25 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 523..546
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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