DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10931 and PAAF1

DIOPT Version :9

Sequence 1:NP_611261.1 Gene:CG10931 / 37024 FlyBaseID:FBgn0034274 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_001350485.1 Gene:PAAF1 / 80227 HGNCID:25687 Length:393 Species:Homo sapiens


Alignment Length:243 Identity:60/243 - (24%)
Similarity:99/243 - (40%) Gaps:51/243 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   105 AWSAAGLIASCSDDMTVRLW-DARSKLCVKVLEGHSRYS--FSCCFNPQANLLASTSFDETVRLW 166
            ||.......|.||..||.:. :..:..|.:..|.....|  .||   |:.|  ||:.|       
Human    29 AWVLTSFFPSYSDLDTVFITSNMIANFCCEPAEWVQTKSIHISC---PKEN--ASSKF------- 81

  Fly   167 DVRTGKTLKIVHAHQDPITSVDFHRDGNIFVTSSYDGLVRLWDSSTGHVLKTLVDVDNIPVGYVK 231
             :....|...:|...  ||.:|....|.:.|:||.||.:::|.:|.|. |:.:::.....|...:
Human    82 -LAPYTTFSRIHTKS--ITCLDISSRGGLGVSSSTDGTMKIWQASNGE-LRRVLEGHVFDVNCCR 142

  Fly   232 FSPNGRYILSSTLNNTLRLWNYKKPKCMRTYRGHLNEFYCSNSNFSTTGGIW----------IVS 286
            |.|:|..:||..::..|::|:.:...|:.|::||             .|||.          :||
Human   143 FFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGH-------------KGGILDTAIVDRGRNVVS 194

  Fly   287 GSEDNTLCIWNLQTRELVQKISTEGDQILSTHCHPTANVIASGALQNS 334
            .|.|.|..:|:......:..::         .|..:.|.:|.||..||
Human   195 ASRDGTARLWDCGRSACLGVLA---------DCGSSINGVAVGAADNS 233

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10931NP_611261.1 WD40 <48..341 CDD:225201 60/243 (25%)
WD40 49..341 CDD:238121 60/243 (25%)
WD40 repeat 59..96 CDD:293791
WD40 repeat 102..137 CDD:293791 8/32 (25%)
WD40 repeat 142..178 CDD:293791 9/37 (24%)
WD40 repeat 185..220 CDD:293791 12/34 (35%)
WD40 repeat 227..263 CDD:293791 10/35 (29%)
WD40 repeat 271..309 CDD:293791 9/47 (19%)
WD40 repeat 314..340 CDD:293791 7/21 (33%)
PAAF1NP_001350485.1 WD40 90..339 CDD:330360 42/169 (25%)
WD40 repeat 96..133 CDD:293791 13/37 (35%)
WD40 repeat 139..175 CDD:293791 9/35 (26%)
WD40 repeat 180..223 CDD:293791 8/51 (16%)
WD40 repeat 232..279 CDD:293791 2/2 (100%)
WD40 repeat 284..318 CDD:293791
WD40 repeat 326..359 CDD:293791
WD40 repeat 366..388 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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