DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10931 and wdsub1

DIOPT Version :9

Sequence 1:NP_611261.1 Gene:CG10931 / 37024 FlyBaseID:FBgn0034274 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_001071237.1 Gene:wdsub1 / 777721 ZFINID:ZDB-GENE-061110-97 Length:487 Species:Danio rerio


Alignment Length:328 Identity:81/328 - (24%)
Similarity:130/328 - (39%) Gaps:94/328 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 IQSLAGHGDGVNDVAWSAAGLIASCSDDMTVRLWDAR--SKLCVKVLEGHSRYSFSCCFNPQANL 153
            |.:|..|.|.||.||:| ..|:|:||.|.::.::.:|  |:|....|.||......|||:.....
Zfish     5 ICTLQSHRDDVNCVAFS-GDLLATCSADKSICVYSSRDFSELPFSPLSGHGYGVHCCCFSACGQY 68

  Fly   154 LASTSFDETVRLWDVRTGKTLKIV-HAHQDPITSVDFHRDGNIFVTSSYDGLVRLWDSSTGHVLK 217
            |||.|.|.|..:|.:.||:...:: |..:.|:....|..|.:..|:...||.:.|||.::..:.:
Zfish    69 LASCSTDATTMVWSMDTGEIEAVLEHPGRSPVRVCAFSPDSSHLVSGGSDGSIALWDFTSRTLRR 133

  Fly   218 TLVDVDNIPVGYVKFSPNGRYILSSTLNNTLRLWNYK--------------------KPKCMRTY 262
            |.| |::..:....|:|.|:..::.:....||||:..                    .||.|:..
Zfish   134 TGV-VNDTSIVACSFTPCGQMFITGSTYGDLRLWDLNMNHLHAEKNAHDLGVSCAQFAPKMMKGT 197

  Fly   263 RGHLNEFYCSNSNFSTTG-----GIWI------------------------------------VS 286
            .|      |.....::.|     .|||                                    ||
Zfish   198 DG------CVQFRLASCGQDSLLKIWIVSLLPSAGIKMQLAHTLTGQSAPVLSCAYSPDGQMLVS 256

  Fly   287 GSEDNTLCIWNLQTRELVQKISTEGDQILSTHCH----------PTANVIASGALQNSYAIKIWK 341
            ||.|.|:.::.          :.||..:.:.|.|          |||.:||:|::..|  :.||:
Zfish   257 GSVDKTVTVYQ----------ADEGVLLYTLHQHDRYVTACAFSPTAPLIATGSMDKS--VNIWR 309

  Fly   342 SSE 344
            ..|
Zfish   310 MEE 312

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10931NP_611261.1 WD40 <48..341 CDD:225201 79/323 (24%)
WD40 49..341 CDD:238121 79/323 (24%)
WD40 repeat 59..96 CDD:293791 2/4 (50%)
WD40 repeat 102..137 CDD:293791 13/36 (36%)
WD40 repeat 142..178 CDD:293791 12/36 (33%)
WD40 repeat 185..220 CDD:293791 9/34 (26%)
WD40 repeat 227..263 CDD:293791 10/55 (18%)
WD40 repeat 271..309 CDD:293791 11/78 (14%)
WD40 repeat 314..340 CDD:293791 9/35 (26%)
wdsub1NP_001071237.1 WD40 4..309 CDD:238121 79/323 (24%)
WD 1 10..47 15/37 (41%)
WD40 repeat 17..52 CDD:293791 12/35 (34%)
WD40 50..>371 CDD:225201 64/282 (23%)
WD 2 52..93 14/40 (35%)
WD40 repeat 58..96 CDD:293791 13/37 (35%)
WD 3 95..134 9/38 (24%)
WD40 repeat 100..134 CDD:293791 8/33 (24%)
WD 4 137..176 8/38 (21%)
WD40 repeat 143..178 CDD:293791 7/34 (21%)
WD 5 179..227 9/53 (17%)
WD40 repeat 184..236 CDD:293791 9/57 (16%)
WD 6 237..276 8/48 (17%)
WD40 repeat 242..278 CDD:293791 8/45 (18%)
WD 7 279..318 11/36 (31%)
WD40 repeat 284..308 CDD:293791 7/25 (28%)
SAM_WDSUB1 343..414 CDD:188904
SAM 344..409 CDD:197735
RING 418..483 CDD:302633
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D957291at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.