DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10931 and WDR38

DIOPT Version :9

Sequence 1:NP_611261.1 Gene:CG10931 / 37024 FlyBaseID:FBgn0034274 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_001263303.1 Gene:WDR38 / 401551 HGNCID:23745 Length:315 Species:Homo sapiens


Alignment Length:281 Identity:80/281 - (28%)
Similarity:138/281 - (49%) Gaps:10/281 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 HSGCVTGLKFSSNGENLVSSSGDRLLKLWDLSATRCIQSLAGHGDGVNDVAWSAAG-LIASCSDD 118
            |.|.|....||.:|:.|::.|.|..:..|:..:.:.:..|.||...|....:|..| |.||.|.|
Human    20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCD 84

  Fly   119 MTVRLWDARSKLCVKVLEGHSRYSFSCCFNPQANLLASTSFDETVRLWDVRTGKTLKIVHAHQDP 183
            .||||||.....|::||:||.|...:..|:|.:..|||..:|:.|.||||::|:.|:::..|:|.
Human    85 CTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDS 149

  Fly   184 ITSVDFHRDGNIFVTSSYDGLVRLWD--SSTGHVLKTLVDVDNIPVGYVKFSPNGRYILSSTLNN 246
            |.|.||....|...|.|:|..|.:||  ..|..|....::..:..:..:.:|.:| .:.|.:.:.
Human   150 IQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASG-LLASGSWDK 213

  Fly   247 TLRLWNYKKPKCMRTYRGHLNEFYCSNSNFSTTGGIWIVSGSEDNTLCIWNLQTRELVQKISTEG 311
            |:.:|.......:...:||:.  :..:..|| ...:|:.|......:.:|:..|.:.::.:. :|
Human   214 TIHIWKPTTSSLLIQLKGHVT--WVKSIAFS-PDELWLASAGYSRMVKVWDCNTGKCLETLK-QG 274

  Fly   312 DQILSTHC--HPTANVIASGA 330
            ...::..|  .|...::.|||
Human   275 VLDVAHTCAFTPDGKILVSGA 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10931NP_611261.1 WD40 <48..341 CDD:225201 80/281 (28%)
WD40 49..341 CDD:238121 80/281 (28%)
WD40 repeat 59..96 CDD:293791 9/36 (25%)
WD40 repeat 102..137 CDD:293791 16/35 (46%)
WD40 repeat 142..178 CDD:293791 13/35 (37%)
WD40 repeat 185..220 CDD:293791 12/36 (33%)
WD40 repeat 227..263 CDD:293791 5/35 (14%)
WD40 repeat 271..309 CDD:293791 6/37 (16%)
WD40 repeat 314..340 CDD:293791 5/19 (26%)
WDR38NP_001263303.1 WD40 <11..299 CDD:225201 80/281 (28%)
WD 1 19..58 10/37 (27%)
WD40 20..301 CDD:238121 80/281 (28%)
WD40 repeat 26..61 CDD:293791 8/34 (24%)
WD 2 61..100 17/38 (45%)
WD40 repeat 67..103 CDD:293791 16/35 (46%)
WD 3 103..142 16/38 (42%)
WD40 repeat 108..144 CDD:293791 13/35 (37%)
WD 4 145..184 14/38 (37%)
WD40 repeat 151..189 CDD:293791 12/37 (32%)
WD 5 190..228 5/38 (13%)
WD40 repeat 195..230 CDD:293791 5/35 (14%)
WD 6 231..272 8/43 (19%)
WD40 repeat 236..272 CDD:293791 6/36 (17%)
WD 7 275..313 5/21 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 295..315 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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