DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10931 and Wdsub1

DIOPT Version :9

Sequence 1:	NP_611261.1	Gene:	CG10931 / 37024	FlyBaseID:	FBgn0034274	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001014201.1	Gene:	Wdsub1 / 362137	RGDID:	1359296	Length:	476	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	74/321 - (23%)
Similarity:	138/321 - (42%)	Gaps:	82/321 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 RCIQSLAGHGDGVNDVAWSAAGLIASCSDDMTVRLWDAR--SKLCVKVLEGHSRYSFSCC-FNPQ 150
            :.|.:||.|||.|:..|:|:. |:|:||.|.|:||:...  ::|....|:.|: |:..|| |:|.
  Rat     3 KLIHTLADHGDDVSCCAFSST-LLATCSLDKTIRLYSLSDFAELPHSPLKFHT-YAVHCCSFSPS 65

  Fly   151 ANLLASTSFDETVRLWDVRTGKTLKIV-HAHQDPITSVDFHRDGNIFVTSSYDGLVRLWDSSTGH 214
            .::|||.|.|.|..||...:|.||.:: .....|:....|..|.....:.:.||.|.||::.:..
  Rat    66 GHVLASCSTDGTTVLWSAHSGHTLTVLEQPGGSPVRVCCFSPDSTYLASGAADGSVVLWNAHSYK 130

  Fly   215 VLKTLVDVDNIPVGYVK--------FSPNGRYILSSTLNNTLRLWNYKKPKCMRTYRGH-LNEFY 270
            :.:         .|.||        |||:|..:::.:....|.:|: .:.:|:.:.:.| |....
  Rat   131 LYR---------CGSVKDSSLVACAFSPDGGLLVTGSSGGDLTVWD-DRMRCLHSEKAHDLGITC 185

  Fly   271 CSNSNFSTTGG-------------------IWIV------------------------------- 285
            ||.|:...:||                   :|:|
  Rat   186 CSFSSQPLSGGEHGLQLYRLASCGQDCEIKLWVVSFTRVLGFELKYRSTLSGHCAPVLACAFSHD 250

  Fly   286 -----SGSEDNTLCIWNLQTRELVQKISTEGDQILSTHCHPTANVIASGALQNSYAIKIWK 341
                 |||.|.::.|:::.|:.::..::.....:.:....|...::|:|::..:  :.||:
  Rat   251 GQMLASGSVDKSVIIYDIGTQSVLHTLTQHTRYVTTCAFAPNTLLLATGSMDKT--VNIWQ 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10931	NP_611261.1	WD40	<48..341	CDD:225201	73/319 (23%)
		WD40	49..341	CDD:238121	73/319 (23%)
		WD40 repeat	59..96	CDD:293791	2/6 (33%)
		WD40 repeat	102..137	CDD:293791	12/36 (33%)
		WD40 repeat	142..178	CDD:293791	15/37 (41%)
		WD40 repeat	185..220	CDD:293791	7/34 (21%)
		WD40 repeat	227..263	CDD:293791	10/43 (23%)
		WD40 repeat	271..309	CDD:293791	13/92 (14%)
		WD40 repeat	314..340	CDD:293791	3/25 (12%)
Wdsub1	NP_001014201.1	WD40	4..309	CDD:238121	73/318 (23%)
		WD 1	10..47		15/37 (41%)
		WD40 repeat	16..52	CDD:293791	12/36 (33%)
		WD 2	52..91		17/39 (44%)
		WD40 repeat	57..93	CDD:293791	15/35 (43%)
		WD 3	95..134		8/47 (17%)
		WD40 repeat	101..136	CDD:293791	7/43 (16%)
		WD 4	137..176		9/39 (23%)
		WD40 repeat	143..177	CDD:293791	7/34 (21%)
		WD 5	178..228		9/49 (18%)
		WD40 repeat	183..236	CDD:293791	7/52 (13%)
		WD 6	237..276		6/38 (16%)
		WD40 repeat	242..266	CDD:293791	4/23 (17%)
		WD 7	279..318		5/33 (15%)
		WD40 repeat	284..308	CDD:293791	3/25 (12%)
		SAM_WDSUB1	328..399	CDD:188904
		U-box	404..476	CDD:398320
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D957291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010