DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10931 and Wdr13

DIOPT Version :9

Sequence 1:	NP_611261.1	Gene:	CG10931 / 37024	FlyBaseID:	FBgn0034274	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_006256781.2	Gene:	Wdr13 / 317370	RGDID:	1560982	Length:	485	Species:	Rattus norvegicus

Alignment Length:	342	Identity:	78/342 - (22%)
Similarity:	141/342 - (41%)	Gaps:	42/342 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 ENSMSPGYA---IKHSLLGH-SGCVTGLKFSSNGEN-LVSSSGDRLLKLWDL--SATRCIQSLAG 96
            :.|:|..||   :.|....| ...|..::|:::..: |...|.|..:.|..|  :....:..|.|
  Rat   151 DTSLSENYAFAGMYHVFDQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLHVLRG 215

  Fly    97 HGDGVNDVAWSAAG-LIASCSDDMTVRLWDARSKLCVKVLEGHSRYSFSCC-FNP-QANLLASTS 158
            |..||:|.|||.:. ::.|.|.|.|:|:|.:....|::.:.........|| |.| ..||....:
  Rat   216 HTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIREIPDPDGAELLCCTFQPVNNNLTVVGN 280

  Fly   159 FDETVRLWDVRTGKTLKIVHAHQDPIT----SVDFHRDGNIFVTSSYDGLV--RLWDSSTGHVLK 217
            ....|.:.::.|||.:|   .....:|    ::.|...|.:.......|.|  .|:|.:||.:.|
  Rat   281 AKHNVHVMNISTGKKVK---GGSSKLTGRVLALSFDAPGRLLWAGDDRGSVFSFLFDMATGKLTK 342

  Fly   218 T--LVDVDNIPV------GYVKFSPNGRYILSSTLNNTLRLW----NYKKPKCMRTY----RGH- 265
            .  ||..:..||      .:|........:|.:...|.|.|:    |....:..|::    ..|
  Rat   343 AKRLVVHEGSPVTSISARSWVSREARDPSLLINACLNKLLLYRVVDNEGALQLKRSFPIEQSSHP 407

  Fly   266 LNEFYCSNSNFSTTGGIWIVSGSEDNTLCIWNLQ--TRELVQKISTEGDQILSTHCHPTANVIAS 328
            :...:|...:|..  |..:|:||||..:..::::  .:..|.|:......:|....:...:::||
  Rat   408 VRSIFCPLMSFRQ--GACVVTGSEDMCVHFFDVERAAKAAVNKLQGHSAPVLDVSFNCDESLLAS 470

  Fly   329 GALQNSYAIKIWKSSEK 345
            .  ..|..:.:|:..:|
  Rat   471 S--DASGMVIVWRREQK 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10931	NP_611261.1	WD40	<48..341	CDD:225201	72/324 (22%)
		WD40	49..341	CDD:238121	72/323 (22%)
		WD40 repeat	59..96	CDD:293791	8/39 (21%)
		WD40 repeat	102..137	CDD:293791	11/35 (31%)
		WD40 repeat	142..178	CDD:293791	11/37 (30%)
		WD40 repeat	185..220	CDD:293791	10/42 (24%)
		WD40 repeat	227..263	CDD:293791	8/49 (16%)
		WD40 repeat	271..309	CDD:293791	10/39 (26%)
		WD40 repeat	314..340	CDD:293791	4/25 (16%)
Wdr13	XP_006256781.2	WD40	<165..485	CDD:225201	73/326 (22%)
		WD40 repeat	221..257	CDD:293791	11/35 (31%)
		WD40 repeat	263..300	CDD:293791	11/39 (28%)
		WD40 repeat	308..347	CDD:293791	9/38 (24%)
		WD40 repeat	354..400	CDD:293791	8/45 (18%)
		WD40 repeat	408..450	CDD:293791	10/43 (23%)
		WD40 repeat	456..480	CDD:293791	4/25 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0266
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900