DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10931 and Wdr27

DIOPT Version :9

Sequence 1:	NP_611261.1	Gene:	CG10931 / 37024	FlyBaseID:	FBgn0034274	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_008757027.1	Gene:	Wdr27 / 308222	RGDID:	1309633	Length:	818	Species:	Rattus norvegicus

Alignment Length:	324	Identity:	69/324 - (21%)
Similarity:	127/324 - (39%)	Gaps:	73/324 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VTGLKFSSNGENLVSSSGDRLLKLWDLSATRCIQSLAGHGDGVNDVAWS-AAGLIASCSDDMTVR 122
            ||.|:||.:|:.|....|:.|..::|.|.:....:.:||...||.|.|| ....:.|.:.|.|:|
  Rat   507 VTCLQFSGDGQQLACGLGNHLSLVFDASLSGAPAAFSGHDGAVNTVCWSHDKRWLLSTARDRTLR 571

  Fly   123 LWDARSKLCVKVLEGHSRYSFSCCFNPQANLLASTSFDETVRLWD---------VRTGKTLKIVH 178
            :|..            .|..|       ..|||:.:|.:.|....         :.:|....::.
  Rat   572 VWSV------------PRTEF-------VMLLAADAFPKPVASAQFYYMDTFILLSSGPEFCLLK 617

  Fly   179 AHQD---------------------PITSV----------DFHRDGNIFVTSSYDGLVRLWDSST 212
            .|.|                     |.||.          ||:  .:|.:|:..|..|.::|.:.
  Rat   618 YHIDLCRDDIRRYKPKSRYKPIFRLPTTSAADITSLSAVNDFY--SHIILTAGRDRTVEVFDLNA 680

  Fly   213 GHVLKTLVDVDNIPVGYVKFSPNGRYI----------LSSTLNNTLRLWNYKKPKCMRTYRGHLN 267
            |.....|.:|.:.||..:..:....:|          |::.:.:.:|||:.:..:|:|.:.||.|
  Rat   681 GCSAAVLAEVHSRPVHRICQNKGSSFIAQQSLAYNLFLTTAVGDGVRLWDLRNLRCVRCFEGHPN 745

  Fly   268 EFYCSNSNFSTTGGIWIVSGSEDNTLCIWNLQTRELVQKISTEGDQILSTHCHPTANVIASGAL 331
            ..|.....||..|.: :..|:||....::.:.:...:.:::...|.:.....:|.|:.:.:..|
  Rat   746 RSYPCGVAFSPCGKL-MACGAEDRHAYVYEMGSSSFLYRLAGHTDTVTEVAFNPAASQLITATL 808

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10931	NP_611261.1	WD40	<48..341	CDD:225201	69/324 (21%)
		WD40	49..341	CDD:238121	69/324 (21%)
		WD40 repeat	59..96	CDD:293791	11/36 (31%)
		WD40 repeat	102..137	CDD:293791	9/35 (26%)
		WD40 repeat	142..178	CDD:293791	7/44 (16%)
		WD40 repeat	185..220	CDD:293791	10/44 (23%)
		WD40 repeat	227..263	CDD:293791	8/45 (18%)
		WD40 repeat	271..309	CDD:293791	6/37 (16%)
		WD40 repeat	314..340	CDD:293791	3/18 (17%)
Wdr27	XP_008757027.1	WD40	<45..229	CDD:421866
		WD40 repeat	67..112	CDD:293791
		WD40 repeat	120..154	CDD:293791
		WD40 repeat	160..193	CDD:293791
		WD40 repeat	204..230	CDD:293791
		WD40	508..815	CDD:421866	68/323 (21%)
		WD40 repeat	508..544	CDD:293791	10/35 (29%)
		WD40 repeat	550..632	CDD:293791	19/100 (19%)
		WD40 repeat	650..688	CDD:293791	8/39 (21%)
		WD40 repeat	696..741	CDD:293791	7/44 (16%)
		WD40 repeat	749..785	CDD:293791	6/36 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0266
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810