DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10931 and WSB1

DIOPT Version :9

Sequence 1:NP_611261.1 Gene:CG10931 / 37024 FlyBaseID:FBgn0034274 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_056441.6 Gene:WSB1 / 26118 HGNCID:19221 Length:421 Species:Homo sapiens


Alignment Length:269 Identity:68/269 - (25%)
Similarity:120/269 - (44%) Gaps:42/269 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 SGCVT----GLKFSSNGENLVSSSGDRLLKLWDLSATRCIQSLAGHGDGVNDVAWSAAG--LIAS 114
            |.||.    ..:|..:...|.:...:..:|:||:...:.:.:|..|.:.|.|:.::..|  ::.|
Human   124 SRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVS 188

  Fly   115 CSDDMTVRLWDARSK-LCVKVLEGHSRYSFSCCFNPQANLLASTSFDETVRLWDVRTGKTLKIVH 178
            .|.|.|:|:||.:.. ..:|||.||..:.:||.|:|.:::|.|....:.|.||::.....::.:.
Human   189 ASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 253

  Fly   179 AHQDPITSVDFHRDGNIFVTSSYDGLVRLWDSSTGHVLKTLVDVDNIP------------VGYVK 231
            .|...:.:.||..||.:..|:|||..|.:||...|.:|.....:...|            |..|.
Human   254 GHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVS 318

  Fly   232 FSPNGRYILSSTLNNTLRLWNYKKPKCMRTYRGHLNEFY------CSNS---NFSTTGGIWIVSG 287
            ||.:|.::.|...:..:|.|             .::|.|      .||.   .|||.|.: :.:|
Human   319 FSHDGLHVASLADDKMVRFW-------------RIDEDYPVQVAPLSNGLCCAFSTDGSV-LAAG 369

  Fly   288 SEDNTLCIW 296
            :.|.::..|
Human   370 THDGSVYFW 378

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10931NP_611261.1 WD40 <48..341 CDD:225201 68/269 (25%)
WD40 49..341 CDD:238121 68/269 (25%)
WD40 repeat 59..96 CDD:293791 7/40 (18%)
WD40 repeat 102..137 CDD:293791 12/37 (32%)
WD40 repeat 142..178 CDD:293791 9/35 (26%)
WD40 repeat 185..220 CDD:293791 13/34 (38%)
WD40 repeat 227..263 CDD:293791 8/35 (23%)
WD40 repeat 271..309 CDD:293791 9/29 (31%)
WD40 repeat 314..340 CDD:293791
WSB1NP_056441.6 WD 1 32..71
WD40 38..382 CDD:225201 68/269 (25%)
WD40 repeat 59..105 CDD:293791
WD 2 124..165 8/40 (20%)
WD40 135..388 CDD:238121 65/258 (25%)
WD 3 168..208 11/39 (28%)
WD40 repeat 174..212 CDD:293791 12/37 (32%)
WD 4 212..251 11/38 (29%)
WD40 repeat 217..253 CDD:293791 9/35 (26%)
WD 5 254..293 14/38 (37%)
WD40 repeat 261..299 CDD:293791 13/37 (35%)
WD 6 309..346 10/49 (20%)
WD40 repeat 314..353 CDD:293791 10/51 (20%)
SOCS_WSB1_SWIP1 382..421 CDD:239715
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.