Protein Alignment CG10931 and POC1A

DIOPT Version :10

• Sequence 1: NP_611261.1
• Gene: CG10931 / 37024
• FlyBaseID: FBgn0034274
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_056241.3
• Gene: POC1A / 25886
• HGNCID: 24488
• Length: 407
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 84/308 - (27%)
• Similarity: 141/308 - (45%)
• Gaps: 27/308 - (8%)

  Fly    47 AIKHSLLGHSGCVTGLKFSSNGENLVSSSGDRLLKLWDLSATRCIQSLAGHGDGVNDVAWSAAG- 110
            :::....||...||.:.||.|.:.|.|.|.|..|.:|.:..........||.|.|..|.:|.:|
Human    10 SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74

  Fly   111 LIASCSDDMTVRLWDARSKLCVKVLEGHSRYSFSCCFNPQANLLASTSFDETVRLWDVRTGKTLK 175
            |:||.|.|.|||:|....|....|...|:....|..|........:.|.|:||::|.....|.|.
Human    75 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLF 139

  Fly   176 IVHAHQDPITSVDFHRDGNIFVTSSYDGLVRLWDSSTGHVLKTLVDVDNIPVGYVKFSPNGRYIL 240
            .:..|.:.:....|..||.:.|::|.|..|:|||.|:...:.:..:.... |.||.|.|:|..|.
Human   140 SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGF-VTYVDFHPSGTCIA 203

  Fly   241 SSTLNNTLRLWNYKKPKCMRTYRGHLNEFYCSNSNFSTTGGIWIVSGSEDNTLCIWNLQTRELVQ 305
            ::.::||:::|:.:..:.::.|:  |:....:..:|..:|. ::::.|.|:||.|.:|.
Human   204 AAGMDNTVKVWDVRTHRLLQHYQ--LHSAAVNGLSFHPSGN-YLITASSDSTLKILDLM------ 259

  Fly   306 KISTEGDQILSTHCHP----------TANVIASGALQNSYAIKIWKSS 343
                ||..:.:.|.|.          |....|||.  :...:.:|||:
Human   260 ----EGRLLYTLHGHQGPATTVAFSRTGEYFASGG--SDEQVMVWKSN 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10931	NP_611261.1	WD40	<47..340	CDD:441893	81/303 (27%)
		WD40 repeat	59..96	CDD:293791	11/36 (31%)
		WD40 repeat	102..137	CDD:293791	14/35 (40%)
		WD40 repeat	142..178	CDD:293791	9/35 (26%)
		WD40 repeat	185..220	CDD:293791	11/34 (32%)
		WD40 repeat	227..263	CDD:293791	10/35 (29%)
		WD40 repeat	271..309	CDD:293791	8/37 (22%)
		WD40 repeat	314..340	CDD:293791	6/35 (17%)
POC1A	NP_056241.3	WD40	<6..298	CDD:441893	81/303 (27%)
		WD 1	17..56		13/38 (34%)
		WD40 repeat	23..59	CDD:293791	10/35 (29%)
		WD 2	59..98		17/38 (45%)
		WD40 repeat	64..100	CDD:293791	15/35 (43%)
		WD 3	101..140		10/38 (26%)
		WD40 repeat	107..140	CDD:293791	9/32 (28%)
		WD 4	143..182		12/38 (32%)
		WD40 repeat	148..184	CDD:293791	11/35 (31%)
		WD 5	185..224		10/39 (26%)
		WD40 repeat	190..226	CDD:293791	10/35 (29%)
		WD 6	227..266		11/49 (22%)
		WD40 repeat	232..255	CDD:293791	6/23 (26%)
		WD 7	269..308		8/35 (23%)