DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10931 and Wdr25

DIOPT Version :9

Sequence 1:NP_611261.1 Gene:CG10931 / 37024 FlyBaseID:FBgn0034274 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_808270.2 Gene:Wdr25 / 212198 MGIID:3045255 Length:535 Species:Mus musculus


Alignment Length:334 Identity:86/334 - (25%)
Similarity:139/334 - (41%) Gaps:30/334 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 FKMPMLPSQFHLENSMSPGYAIKHSLLGHSGCVTGLKFS---SNGENLVSSSGDRLLKLWD-LSA 87
            |..|.|.||:  ..:..|...:.| |.||.|.|..:::.   .....|:|:|.|:..|:|: :.:
Mouse   211 FIQPYLNSQY--RETTVPKKVLFH-LRGHRGPVNSIQWCPVFCKSHMLLSASMDKTFKVWNAVDS 272

  Fly    88 TRCIQSLAGHGDGVNDVAWSAAG-LIASCSDDMTVRLWDARSKLCVKVLEGHSRYSFSCC-FNPQ 150
            ..|:|:.:.|.:.|....||..| .|.|...|..:.|.|..:.  .:|..|.|.:..:.. |:|:
Mouse   273 GHCLQTYSVHSEAVRAARWSPCGRRILSGGFDFALHLTDLETG--TQVFSGQSDFRVTTLKFHPK 335

  Fly   151 -ANLLASTSFDETVRLWDVRTGKTLKIVHAHQDPITSVDFHRDGNIFVTS-------SYDGLVRL 207
             .|:.....|...::.||:||||.:|...|.......:.|.::|:.|::|       |.|..:..
Mouse   336 DHNVFLCGGFSSEIKAWDMRTGKVVKGYKATIQQTLDILFLQEGSEFLSSTDASTRDSADRTIIA 400

  Fly   208 WDSSTGHVLKTLVDVDNIPVGYVKFSPNGRYILSSTLNNTLRL----WNYKKPKCMRTYRGHLNE 268
            ||..|...:...:..:......:...|.....|:.|..|.|.|    |.|:..: .|.|.||..|
Mouse   401 WDFRTAAKISNQIFHERYTCPSLALHPREPVFLAQTNGNYLALFSSVWPYRMSR-RRRYEGHKVE 464

  Fly   269 FYCSNSNFSTTGGIWIVSGSEDNTLCIWNLQTRELVQKISTEGDQILSTHCHPTANVIAS--GAL 331
            .|......|..|.: :|:||.|..:.:::.:|......:.......|.|..||   |:.|  |..
Mouse   465 GYAVGCECSPCGDL-LVTGSADGRVLMFSFRTASRACTLQGHTQACLGTTYHP---VLPSVLGTC 525

  Fly   332 QNSYAIKIW 340
            .....||||
Mouse   526 SWGGDIKIW 534

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10931NP_611261.1 WD40 <48..341 CDD:225201 80/313 (26%)
WD40 49..341 CDD:238121 80/312 (26%)
WD40 repeat 59..96 CDD:293791 9/40 (23%)
WD40 repeat 102..137 CDD:293791 9/35 (26%)
WD40 repeat 142..178 CDD:293791 11/37 (30%)
WD40 repeat 185..220 CDD:293791 9/41 (22%)
WD40 repeat 227..263 CDD:293791 9/39 (23%)
WD40 repeat 271..309 CDD:293791 7/37 (19%)
WD40 repeat 314..340 CDD:293791 9/27 (33%)
Wdr25NP_808270.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..108
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 141..160
WD40 230..534 CDD:238121 78/311 (25%)
WD 1 235..277 11/41 (27%)
WD40 repeat 242..281 CDD:293791 8/38 (21%)
WD 2 281..320 11/40 (28%)
WD40 repeat 287..321 CDD:293791 9/35 (26%)
WD 3 321..362 12/40 (30%)
WD40 repeat 327..364 CDD:293791 11/36 (31%)
WD 4 365..411 10/45 (22%)
WD40 repeat 371..413 CDD:293791 9/41 (22%)
WD 5 415..454 8/38 (21%)
WD40 repeat 420..459 CDD:293791 9/39 (23%)
WD 6 460..501 11/41 (27%)
WD40 repeat 467..503 CDD:293791 7/36 (19%)
WD 7 504..535 11/34 (32%)
WD40 repeat 509..534 CDD:293791 9/27 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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