DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10931 and WDSUB1

DIOPT Version :9

Sequence 1:NP_611261.1 Gene:CG10931 / 37024 FlyBaseID:FBgn0034274 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_001121684.1 Gene:WDSUB1 / 151525 HGNCID:26697 Length:476 Species:Homo sapiens


Alignment Length:312 Identity:74/312 - (23%)
Similarity:133/312 - (42%) Gaps:64/312 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    89 RCIQSLAGHGDGVNDVAWSAAGLIASCSDDMTVRLWDAR--SKLCVKVLEGHSRYSFSCCFNPQA 151
            :.|.:||.|||.||..|:|.: |:|:||.|.|:||:..|  ::|....|:.|:.....|||:|..
Human     3 KLIHTLADHGDDVNCCAFSFS-LLATCSLDKTIRLYSLRDFTELPHSPLKFHTYAVHCCCFSPSG 66

  Fly   152 NLLASTSFDETVRLWDVRTGKTLKIVHAHQ-DPITSVDFHRDGNIFVTSSYDGLVRLWDSSTGHV 215
            ::|||.|.|.|..||:...|:.|.::.... .|:....|..|.....:.:.||.|.||::.: :.
Human    67 HILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQS-YK 130

  Fly   216 LKTLVDVDNIPVGYVKFSPNGRYILSSTLNNTLRLWNYKKPKCMRTYRGH-LNEFYCSNSNFSTT 279
            |.....|.:..:....|||||.:.::.:....|.:|: .|.:|:.:.:.| |....|..|:...:
Human   131 LYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWD-DKMRCLHSEKAHDLGITCCDFSSQPVS 194

  Fly   280 GG-------------------IWI------------------------------------VSGSE 289
            .|                   |||                                    ||||.
Human   195 DGEQGLQFFRLASCGQDCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLACAFSHDGQMLVSGSV 259

  Fly   290 DNTLCIWNLQTRELVQKISTEGDQILSTHCHPTANVIASGALQNSYAIKIWK 341
            |.::.:::..|..::..::.....:.:....|...::|:|::..:  :.||:
Human   260 DKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLATGSMDKT--VNIWQ 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10931NP_611261.1 WD40 <48..341 CDD:225201 73/310 (24%)
WD40 49..341 CDD:238121 73/310 (24%)
WD40 repeat 59..96 CDD:293791 2/6 (33%)
WD40 repeat 102..137 CDD:293791 14/36 (39%)
WD40 repeat 142..178 CDD:293791 14/35 (40%)
WD40 repeat 185..220 CDD:293791 8/34 (24%)
WD40 repeat 227..263 CDD:293791 9/35 (26%)
WD40 repeat 271..309 CDD:293791 12/92 (13%)
WD40 repeat 314..340 CDD:293791 3/25 (12%)
WDSUB1NP_001121684.1 WD40 <2..308 CDD:225201 72/309 (23%)
WD40 4..309 CDD:238121 73/309 (24%)
WD 1 10..47 17/37 (46%)
WD40 repeat 16..52 CDD:293791 14/36 (39%)
WD 2 52..91 15/38 (39%)
WD40 repeat 57..93 CDD:293791 14/35 (40%)
WD 3 95..134 9/39 (23%)
WD40 repeat 101..135 CDD:293791 8/34 (24%)
WD 4 137..176 10/39 (26%)
WD40 repeat 142..177 CDD:293791 9/35 (26%)
WD 5 178..228 8/49 (16%)
WD40 repeat 183..236 CDD:293791 6/52 (12%)
WD 6 237..276 6/38 (16%)
WD40 repeat 242..266 CDD:293791 5/23 (22%)
WD 7 279..318 5/33 (15%)
WD40 repeat 284..326 CDD:293791 5/28 (18%)
SAM_WDSUB1 328..399 CDD:188904
SAM 332..395 CDD:197735
U-box 404..476 CDD:252675
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D957291at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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